Evidence map›Paper›PMID 36050558›Full record

ArticleIntensive care medicine2022

Compartmentalisation of immune responses in critical illness: does it matter?

Andrew Conway Morris, Jennifer Rynne, Manu Shankar-Hari

Abstract read
In one paragraph

Article in Intensive care medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Biomarkers in lower respiratory tract samples in the diagnosis of ventilator-associated pneumonia: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2025
    Pooled it
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  18. Observational
  19. Multi-Omics and -Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  20. Hemoadsorption in septic shock - CON.Intensive care medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Andrew Conway MorrisDivision of Anaesthesia, Department of Medicine, University of Cambridge, Level 4 Addenbrooke's Hospital, Hills Road, Cambridge, CB2 0QQ, UK. ac926@cam.ac.uk.ORCID http://orcid.org/0000-0002-3211-3216
Jennifer RynneCentre for Inflammation Research, Edinburgh BioQuarter, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0002-8945-8434
Manu Shankar-HariCentre for Inflammation Research, Edinburgh BioQuarter, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh, EH16 4TJ, UK.ORCID http://orcid.org/0000-0002-5338-2538

Funding

Medical Research Council MR/V006118/1
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Critical IllnessImmunityHumans

Identifiers

PMID36050558
PMCPMC9436168

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.