Evidence map›Paper›PMID 36051892›Full record

ArticleJCSM clinical reports2020

Effects of a lifestyle intervention on body composition in prostate cancer patients on androgen deprivation therapy.

Zachary L Chaplow, Brian C Focht, Alexander R Lucas, Elizabeth Grainger, Christina Simpson, Jackie Buell, Ciaran M Fairman, Jennifer M Thomas-Ahner, Jessica Bowman, Victoria R DeScenza and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JCSM clinical reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Zachary L ChaplowKinesiology, Department of Human Sciences, The Ohio State University, 305 Annie and John Glenn Ave, Columbus, OH 43210, USA.
Brian C FochtKinesiology, Department of Human Sciences, The Ohio State University, 305 Annie and John Glenn Ave, Columbus, OH 43210, USA.ORCID 0000-0003-2233-4768
Alexander R LucasDepartment of Health Behavior and Policy, Virginia Commonwealth University, Richmond, VA, USA.
Elizabeth GraingerComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Christina SimpsonComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Jackie BuellMedical Dietetics, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH 43210, USA.
Ciaran M FairmanExercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia.
Jennifer M Thomas-AhnerComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Jessica BowmanKinesiology, Department of Human Sciences, The Ohio State University, 305 Annie and John Glenn Ave, Columbus, OH 43210, USA.
Victoria R DeScenzaKinesiology, Department of Human Sciences, The Ohio State University, 305 Annie and John Glenn Ave, Columbus, OH 43210, USA.
J Paul MonkComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Amir MortazaviComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
Steven K ClintonComprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA.
The Ohio State University · USEdith Cowan University · AUOhio Department of Health · USVirginia Commonwealth University · US

Funding

NCI NIH HHS R03 CA162969
6 · The paper itself

Abstract

Background: Exercise and dietary (EX+D) interventions could represent an optimal treatment for attenuating or reversing adverse effects of androgen deprivation therapy (ADT) in prostate cancer (PCa) patients. The Individualized Diet and Exercise Adherence-Pilot (IDEA-P) trial compared the effects of an EX+D intervention relative to standard-of-care (SC) treatment among PCa patients undergoing ADT. The present study evaluated the effects of the EX+D intervention on body composition (BC) obtained via dual-energy X-ray absorptiometry (DXA) in a subsample of IDEA-P patients. A secondary objective was to explore the association of adiposity and lean mass with mobility performance and strength. Methods: Complete DXA data were acquired from a subsample of 22 PCa patients (EX+D: Results: Intention-to-treat analysis revealed EX+D resulted in significant improvements in fat mass ( Conclusions: Findings suggest the EX+D intervention resulted in superior preservation of lean tissue and improvement in adiposity relative to SC treatment. Results underscore the utility of implementing EX+D interventions for preserving muscle mass and reducing adiposity in PCa patients undergoing ADT.

Indexed as

Androgen deprivationBody compositionDietExerciseHormone therapyProstate cancer

Identifiers

PMID36051892
PMCPMC9432850
OpenAlexW3028698380

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.