Evidence map›Paper›PMID 36052289›Full record

ArticleBone reports2022

Five-year risk of fracture and subsequent fractures among adults with cerebral palsy.

Daniel G Whitney, Gregory A Clines, Aleda M Leis, Michelle S Caird, Edward A Hurvitz

Open access · goldAbstract read
In one paragraph

Article in Bone reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Daniel G WhitneyDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
Gregory A ClinesDivision of Metabolism, Endocrinology & Diabetes, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.
Aleda M LeisEpidemiology Department, University of Michigan, Ann Arbor, MI, USA.
Michelle S CairdDepartment of Orthopaedic Surgery, University of Michigan, Ann Arbor, MI, USA.
Edward A HurvitzDepartment of Physical Medicine and Rehabilitation, University of Michigan, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · USAnn Arbor VA Medical Center · US

Funding

Addressing knowledge gaps by multi-level research design to optimize clinical trial development in order to reduce fracture burden for adults with neurodevelopmental disabilitiesR01AR076994 · NIAMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HURVITZ, EDWARD A · 2021 to 2023
$616k
NIAMS NIH HHS R01 AR076994
6 · The paper itself

Abstract

Background: Epidemiologic evidence documenting the incidence of fracture and subsequent fractures among adults with cerebral palsy (CP) is lacking, which could inform fracture prevention efforts. The objective was to characterize the 5-year rate of initial and subsequent fragility fractures among adults with CP. Methods: This retrospective cohort study used Medicare claims from 01/01/2008-12/31/2019 from adults ≥18 years old with CP ( Results: The IR of fragility fracture at any site over the 5-year follow-up was similar for 18-30-year-old men with CP (IR = 5.2; 95%CI = 4.4-5.9) and 30-34-year-old women with CP (IR = 6.3; 95%CI = 5.3-7.2) compared to the same sex youngest-old (65-74 years old) without CP (IRR = 1.09 and 0.94, respectively, both Conclusion: Young and middle-aged adults with CP had similar-to-worse initial and subsequent fragility fracture profiles compared to the general elderly population- a well characterized group for bone fragility. Findings emphasize the need for fracture prevention efforts at younger ages for CP, possibly by ~5 decades younger.

Indexed as

Cerebral palsyCI, confidence intervalCP, cerebral palsyFractureICD, International Classification of Diseases, Ninth or Tenth Revision, Clinical ModificationIR, incidence rateIRR, incidence rate ratioPreventionSubsequent fracture

Identifiers

PMID36052289
PMCPMC9424353
OpenAlexW4293280787

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.