Evidence map›Paper›PMID 36053227›Full record

ArticleNanoscale2022

Polymer-tethered glycosylated gold nanoparticles recruit sialylated glycoproteins into their protein corona, leading to off-target lectin binding.

Ashfaq Ahmad, Panagiotis G Georgiou, Alessia Pancaro, Muhammad Hasan, Inge Nelissen, Matthew I Gibson

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nanoscale, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Ashfaq AhmadDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL, Coventry, UK. m.i.gibson@warwick.ac.uk.ORCID http://orcid.org/0000-0002-2656-5689
Panagiotis G GeorgiouDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL, Coventry, UK. m.i.gibson@warwick.ac.uk.ORCID http://orcid.org/0000-0001-8968-1057
Alessia PancaroHealth Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, Mol, BE-2400, Belgium.ORCID http://orcid.org/0000-0003-4586-3531
Muhammad HasanDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL, Coventry, UK. m.i.gibson@warwick.ac.uk.ORCID http://orcid.org/0000-0003-3201-7184
Inge NelissenHealth Unit, Flemish Institute for Technological Research (VITO), Boeretang 200, Mol, BE-2400, Belgium.
Matthew I GibsonDepartment of Chemistry, University of Warwick, Gibbet Hill Road, CV4 7AL, Coventry, UK. m.i.gibson@warwick.ac.uk.ORCID http://orcid.org/0000-0002-8297-1278
University of Warwick · GBFlemish Institute for Technological Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Upon exposure to biological fluids, the fouling of nanomaterial surfaces results in non-specific capture of proteins, which is particularly important when in contact with blood for

Indexed as

Metal NanoparticlesNanoparticlesProtein CoronaGalactoseGlycoproteinsGoldLectinsPolymersPolysaccharidesProtein BindingSerum Albumin, BovineSialic Acid Binding Ig-like Lectin 2Sialic AcidsGalactoseGlycoproteinsGoldLectinsPolymersPolysaccharidesProtein CoronaSerum Albumin, BovineSialic Acid Binding Ig-like Lectin 2Sialic Acids

Identifiers

PMID36053227
PMCPMC9494357
OpenAlexW4293659954

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.