Evidence map›Paper›PMID 36055920›Full record

ArticleValue in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research2023

Preferences for Sexually Transmitted Infection and Cancer Vaccines in the United States and in China.

Abram L Wagner, Yihan Lu, Cara B Janusz, Stephen W Pan, Brian Glover, Zhenke Wu, Lisa A Prosser

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Abram L WagnerDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA. Electronic address: awag@umich.edu.
Yihan LuDepartment of Epidemiology, Ministry of Education Key Laboratory of Public Health Safety, Fudan University School of Public Health, Shanghai, China.
Cara B JanuszSusan B. Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
Stephen W PanDepartment of Health and Environmental Sciences, Xi'an Jiaotong-Liverpool University, Suzhou, China.
Brian GloverDepartment of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Zhenke WuDepartment of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, MI, USA.
Lisa A ProsserSusan B. Meister Child Health Evaluation and Research Center, Department of Pediatrics, University of Michigan Medical School, Ann Arbor, MI, USA.
University of Michigan–Ann Arbor · USFudan University · CNXi’an Jiaotong-Liverpool University · CN

Funding

Characterizing parental beliefs to support optimization of vaccine introductionK01AI137123 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI WAGNER, ABRAM LUTHER · 2019 to 2023
$475k
NIAID NIH HHS K01 AI137123
6 · The paper itself

Abstract

objectivesThis study assessed preferences for hypothetical vaccines for children in 2 large vaccine markets according to how the vaccine-preventable disease is transmitted via a discrete choice experiment.

methodsSurveys in China (N = 1350) and the United States (N = 1413) were conducted from April to May 2021. The discrete choice experiment included attributes of cost, age at vaccination, transmission mode of the vaccine-preventable disease, and whether the vaccine prevents cancer. Preference utilities were modeled in a Bayesian, multinomial logistic regression model, and respondents were grouped by vaccine preference classification through a latent class analysis.

resultsIndividuals favored vaccines against diseases with transmission modes other than sexual transmission (vaccine for sexually transmitted infection [STI] vs airborne disease, in the United States, odds ratio 0.71; 95% credible interval 0.64-0.78; in China, odds ratio 0.76; 95% credible interval 0.69-0.84). The latent class analysis revealed 6 classes: vaccine rejecters (19% in the United States and 8% in China), careful deciders (18% and 17%), preferring cancer vaccination (20% and 19%), preferring vaccinating children at older ages (10% and 11%), preferring vaccinating older ages, but indifferent about cancer vaccines (23% and 25%), and preferring vaccinating children at younger ages (10% and 19%). Vaccine rejection was higher with age in the United States versus more vaccine rejection among those at the age of 18 to 24 and ≥ 64 years in China.

conclusionThe public had strong preferences against giving their child an STI vaccine, and the class preferring a cancer vaccine was less accepting of an STI vaccine. Overall, this study points to the need for more education about how some STI vaccines could also prevent cancers.

Indexed as

Cancer VaccinesNeoplasmsSexually Transmitted DiseasesVaccine-Preventable DiseasesBayes TheoremChildChinaHumansMiddle AgedUnited StatesVaccinationCancer Vaccinesconjoint analysishuman papillomavirus vaccinesimmunization programslatent class analysisstated choice experimentsurveys and questionnaires

Identifiers

PMID36055920
PMCPMC9908821
OpenAlexW4293738808

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.