Evidence map›Paper›PMID 36056748›Full record

ReviewReviews in medical virology2023

Testosterone and Covid-19: An update.

Aksam Yassin, Ridwan Shabsigh, Raed M Al-Zoubi, Omar M Aboumarzouk, Mustafa Alwani, Joanne Nettleship, Daniel Kelly

Open access · hybridAbstract readReview
In one paragraph

Review in Reviews in medical virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Testosterone and Covid-19: An update.Reviews in medical virology · 2023
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 5 countries.

Aksam YassinSurgical Research Section, Hamad Medical Corporation, Doha, Qatar.
Ridwan ShabsighDepartment of Surgery, St. Barnabas Hospital, Bronx, New York, USA.
Raed M Al-ZoubiSurgical Research Section, Hamad Medical Corporation, Doha, Qatar.
Omar M AboumarzoukSurgical Research Section, Hamad Medical Corporation, Doha, Qatar.
Mustafa AlwaniSurgical Research Section, Hamad Medical Corporation, Doha, Qatar.
Joanne NettleshipDepartment of Oncology and Metabolism, Medical School, University of Sheffield, Sheffield, UK.
Daniel KellyDepartment of Oncology and Metabolism, Medical School, University of Sheffield, Sheffield, UK.ORCID 0000-0002-7463-0692
Hamad Medical Corporation · QACornell University · USDresden International University · DEJordan University of Science and Technology · JOSheffield Hallam University · GBUniversity of Sheffield · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is overwhelming evidence to suggest that male gender is at a higher risk of developing more severe Covid-19 disease and thus having poorer clinical outcomes. However, the relationship between testosterone (T) and Covid-19 remains unclear with both protective and deleterious effects on different aspects of the disease suggested. Here, we review the current epidemiological and biological evidence on the role of testosterone in the process of SARS-CoV-2 infection and in mediating Covid-19 severity, its potential to serve as a biomarker for risk stratification and discuss the possibility of T supplementation as a treatment or preventative therapy for Covid-19.

Indexed as

COVID-19HumansMaleSARS-CoV-2TestosteroneTestosteroneprostatesexual medicinetestosterone

Identifiers

PMID36056748
PMCPMC9537909
OpenAlexW4294376232

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.