SynthesisEuropean psychiatry : the journal of the Association of European Psychiatrists2022
European Psychiatric Association guidance on assessment of cognitive impairment in schizophrenia.
Synthesis in European psychiatry : the journal of the Association of European Psychiatrists, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07759895 (Combination Therapy of Deferiprone and N-Acetylcysteine for Treating Negative Symptoms in Schizophrenia), which is not on this map. Cited by 64 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Combination Therapy of Deferiprone and N-Acetylcysteine for Treating Negative Symptoms in Schizophrenia
Who cites it
64 citing papers in PubMed, 5 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Exploring the Relationship between Cognitive Performance, Performance-Based Functioning, and Everyday Functioning in People with Schizophrenia: a Systematic Literature Review.Schizophrenia bulletin · 2026Pooled it
- Artificial Intelligence in Schizophrenia Spectrum Disorders: Current Use and Future Perspectives. A Systematic Mapping Literature Review.Alpha psychiatry · 2026Pooled it
- The Effects of Cognitive Remediation on Negative Symptoms in Schizophrenia-Spectrum Illness: A Meta-analytic Investigation of Efficacy.Schizophrenia bulletin · 2025Pooled it
- Examining associations, moderators and mediators between childhood maltreatment, social functioning, and social cognition in psychotic disorders: a systematic review and meta-analysis.Psychological medicine · 2023Pooled it
- Age-matched versus non-age-matched comparison of clinical and functional differences between delusional disorder and schizophrenia: a systematic review.Frontiers in psychiatry · 2023Pooled it
- Examination on the Acceptability, Feasibility and Effectiveness of a Digital Cognitive Training Software in Patients With Stable Schizophrenia in China.Neuropsychiatric disease and treatment · 2025Trial
- Hippocampal small RNAs from patients with schizophrenia induce specific cognitive and neural phenotypes in mice.Cell death discovery · 2026Article
- Article
- Understanding the burden of cognitive impairment associated with schizophrenia: Results from the international LUCIA study.European psychiatry : the journal of the Association of European Psychiatrists · 2026Article
- Who Should Decide the Outcome for a Clinical Trial? Comparing the Views of Stakeholders on Intervention Benefit Using Multi-Criteria Decision Modelling of Cognitive Remediation.Schizophrenia bulletin · 2026Article
- Acceptability of the Cardiff Online Cognitive Assessment for Clinical Screening of Patients With Psychosis: Protocol for a Mixed Methods Study.JMIR research protocols · 2026Article
- Diagnosis and management of cognitive impairment associated with schizophrenia: Real-world evidence from a cross-sectional survey of psychiatrists.Schizophrenia research. Cognition · 2026Article
- Virtual reality-based cognitive remediation in severe mental illness: Current evidence from a narrative review.Schizophrenia research. Cognition · 2026Review
- Overcoming Patient Access Barriers in Complex Conditions: Lessons from Schizophrenia for Broader Healthcare Applications.Journal of market access & health policy · 2026Article
- Self-report Assessment of Metacognition Among Schizophrenia Patients: A Systematic Review.Indian journal of psychological medicine · 2026Review
- Social cognitive deficits and their relationship with clinical symptoms in schizophrenia.Schizophrenia (Heidelberg, Germany) · 2026Article
- Application of a cognitive-structure framework-based scenario-based education programme in schizophrenia patients with delusional symptoms: a randomised controlled trial.Frontiers in psychiatry · 2026Article
- Electroconvulsive therapy and autobiographical memory.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026Article
- Applications of Artificial Intelligence Technologies in Nursing for Noncommunicable Chronic Diseases: A Scoping Review.Journal of nursing management · 2026Article
- Improving care for cognitive impairment in schizophrenia: current perspectives and opportunities in Portugal (a consensus development conference).Frontiers in psychiatry · 2026Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 6 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundImpairment in a wide range of cognitive abilities has been consistently reported in individuals with schizophrenia. Both neurocognitive and social cognitive deficits are thought to underlie severe functional disabilities associated with schizophrenia. Despite the key role in schizophrenia outcome, cognition is still poorly assessed in both research and clinical settings.
methodsIn this guidance paper, we provide a systematic review of the scientific literature and elaborate several recommendations for the assessment of cognitive functions in schizophrenia both in research settings and in real-world clinical practice.
resultsExpert consensus and systematic reviews provided guidance for the optimal assessment of cognitive functions in schizophrenia. Based on the reviewed evidence, we recommend a comprehensive and systematic assessment of neurocognitive and social cognitive domains in schizophrenia, in all phases of the disorder, as well as in subjects at risk to develop psychosis. This European Psychiatric Association guidance recommends not only the use of observer reports but also self-reports and interview-based cognitive assessment tools. The guidance also provides a systematic review of the state of the art of assessment in the first episode of psychosis patients and in individuals at risk for psychosis.
conclusionThe comprehensive review of the evidence and the recommendations might contribute to advance the field, allowing a better cognitive assessment, and avoiding overlaps with other psychopathological dimensions. The dissemination of this guidance paper may promote the development of shared guidelines concerning the assessment of cognitive functions in schizophrenia, with the purpose to improve the quality of care and to obtain recovery.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.