SynthesisFrontiers in nutrition2022
Dietary consumption of cruciferous vegetables and bladder cancer risk: A systematic review and meta-analysis.
Synthesis in Frontiers in nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
4 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Cruciferous vegetables intake reduces pancreatic cancer risk: an updated systematic review with meta-analysis.European journal of nutrition · 2024Pooled it
- Broccoli Consumption and Risk of Cancer: An Updated Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2024Pooled it
- Article
- Sulforaphane and bladder cancer: a potential novel antitumor compound.Frontiers in pharmacology · 2023Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Previous studies on the association of cruciferous vegetables intake with bladder cancer risk have reported inconsistent results. We performed the present meta-analysis to summarize evidence on this association and to quantify the potential dose-response relation based on all available cohort studies. Methods: A comprehensive literature search of relevant articles up to March 2022 was performed in PubMed and EMBASE. The summary risk estimates with 95% confidence intervals for the highest vs. the lowest intake of cruciferous vegetables were calculated. Dose-response meta-analysis was also performed for studies reporting categorical risk estimates for at least three quantitative levels of cruciferous vegetables intake. Results: We found that the highest cruciferous vegetables intake was not significantly associated with a lower risk of bladder cancer, compared with the lowest cruciferous vegetables intake category (RR = 0.92, 95% CI 0.80-1.06). Linear dose-response meta-analysis indicated that the pooled RRs for 10 g/day or 1 servings/week increment of cruciferous vegetables intake was not significantly associated with a reduced risk of bladder cancer ( Conclusion: The results of this study did not support the hypothesis that dietary cruciferous vegetables intake was associated with a lower risk of bladder cancer. Further large prospective cohort studies are warranted to confirm our preliminary findings.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.