Evidence map›Paper›PMID 36062883›Full record

ArticlePhysiological genomics2022

Blood pressure and the kidney cortex transcriptome response to high-sodium diet challenge in female nonhuman primates.

Angelica M Riojas, Kimberly D Reeves, Robert E Shade, Sobha R Puppala, Clinton L Christensen, Shifra Birnbaum, Jeremy P Glenn, Cun Li, Hossam Shaltout, Shannan Hall-Ursone and 1 more

Open access · greenAbstract read
In one paragraph

Article in Physiological genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Angelica M RiojasMolecular Medicine and Translational Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0002-4918-407X
Kimberly D ReevesCenter for Precision Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Robert E ShadeSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.
Sobha R PuppalaCenter for Precision Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Clinton L ChristensenMolecular Services Core, Texas Biomedical Research Institute, San Antonio, Texas.
Shifra BirnbaumMolecular Services Core, Texas Biomedical Research Institute, San Antonio, Texas.
Jeremy P GlennMolecular Services Core, Texas Biomedical Research Institute, San Antonio, Texas.
Cun LiDepartment of Animal Science, University of Wyoming, Laramie, Wyoming.
Hossam ShaltoutHypertension and Vascular Research Center, Wake Forest School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0001-7948-3815
Shannan Hall-UrsoneSouthwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, Texas.
Laura A CoxCenter for Precision Medicine, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, North Carolina.ORCID 0000-0002-8836-3783
Texas Biomedical Research Institute · USWake Forest University · USUniversity of Wyoming · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Angiotensin, Sodium and Genes in Primate HypertensionR01HL068180 · NHLBI · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI SHADE, ROBERT E · 2002 to 2005
$2.1M
EXTRAMURAL RES FACILITIES CONSTRC06RR015456 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI VANDEBERG, JOHN L · 2001 to 2001
$1.1M
MOLECULAR AND BIOCHEMICAL GENETICS LABORATORY RENOVATIONC06RR013556 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI SHADE, ROBERT E · 1998 to 1998
–
NCRR NIH HHS C06 RR013556NCRR NIH HHS C06 RR015456NHLBI NIH HHS R01 HL068180NIH HHS P51 OD011133ODCDC CDC HHS P51 OD011133
6 · The paper itself

Abstract

Blood pressure (BP) is influenced by genetic variation and sodium intake with sex-specific differences; however, studies to identify renal molecular mechanisms underlying the influence of sodium intake on BP in nonhuman primates (NHP) have focused on males. To address the gap in our understanding of molecular mechanisms regulating BP in female primates, we studied sodium-naïve female baboons (

Indexed as

HypertensionSodium, DietaryAnimalsBlood PressureDietFemaleHumansKidneyKidney CortexMalePapioSodiumSodium Chloride, DietaryTranscriptomeSodiumSodium Chloride, DietarySodium, Dietarygeneticshypertensionkidneysalt-sensitiveWGCNA

Identifiers

PMID36062883
PMCPMC9639778
OpenAlexW4294671660

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.