Evidence map›Paper›PMID 36064628›Full record

ArticleTrials2022

Protocol for the development of a core domain set for individuals with ankle osteoarthritis.

Sultan Ayyadah Alanazi, Bill Vicenzino, Christiaan J A van Bergen, David J Hunter, Erik A Wikstrom, Hylton B Menz, Yvonne M Golightly, Michelle D Smith

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Sultan Ayyadah AlanaziThe University of Queensland, School of Health and Rehabilitation Sciences: Physiotherapy, Brisbane, Australia.
Bill VicenzinoThe University of Queensland, School of Health and Rehabilitation Sciences: Physiotherapy, Brisbane, Australia.
Christiaan J A van BergenDepartment of Orthopedic Surgery, Amphia, Breda, the Netherlands.
David J HunterSydney Musculoskeletal Health, Kolling Institute, The University of Sydney, Sydney, Australia.
Erik A WikstromMOTION Science Institute, Department of Exercise and Sport Science, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Hylton B MenzDiscipline of Podiatry, School of Allied Health, Human Services and Sport, La Trobe University, Melbourne, Victoria, Australia.
Yvonne M GolightlyCollege of Allied Health Professionals, University of Nebraska Medical Center, Omaha, NE, USA.
Michelle D SmithThe University of Queensland, School of Health and Rehabilitation Sciences: Physiotherapy, Brisbane, Australia. m.smith5@uq.edu.au.ORCID http://orcid.org/0000-0002-7860-1581
The University of Queensland · AUUniversity of North Carolina at Chapel Hill · USErasmus MC · NLLa Trobe University · AUThe University of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnkle osteoarthritis (OA) is a debilitating health condition that is increasing in prevalence. Currently, there are no evidence-based guidelines for managing ankle OA. One of the current challenges to establishing guidelines is the lack of a widely agreed-upon set of outcome measures that are consistently used in ankle OA research. Without a set of agreed-upon outcome measures, it is difficult to synthesise clinical trial outcomes through meta-analysis-an essential element of evidence-informed practice. In order to develop an appropriate set of outcome measures for ankle OA, it is important first to develop a core domain set. In this protocol, we describe the methodological approach that we will use to develop such a core domain set for ankle OA.

methodsWe established an international steering committee to guide the development of a core domain set for ankle OA. The core domain set development will follow a multi-staged approach consisting of three phases, involving participation by patients and clinicians/healthcare professionals. In phase 1, a list of candidate domains will be gleaned from (a) a scoping review of outcome measures used in ankle OA research, (b) qualitative interviews with individuals with ankle OA, and (c) qualitative interviews with healthcare professionals with expertise in ankle OA. In phase 2, the steering committee will review and generate a list of candidate domains from those gleaned in phase 1. In phase 3, this list of candidate domains will be considered in a Delphi process to reach a consensus on a core domain set. We anticipated this will involve 3 rounds of surveys.

conclusionThis protocol describes the methods that will be used to develop a core domain set of health-related aspects for ankle OA. Importantly, it will include both healthcare professional and patient involvement. This is a prerequisite step to developing a core outcome set for ankle OA that should be reported in all clinical trials for ankle OA. The findings will be widely disseminated across peer-refereed publication(s) and national and international conferences, as well as via relevant professional societies, patient support group organisations, and social media platforms. PROJECT REGISTRATION: This project is registered with the Core Outcome Measures in Effectiveness Trials (COMET) database on 17 March 2021. https://www.comet-initiative.org/Studies/Details/1837 .

Indexed as

AnkleOsteoarthritisClinical Trials as TopicConsensusHumansMeta-Analysis as TopicAnkle OsteoarthritisConsensusCore domain setCore outcome setDelphi surveyPatient-reported outcome measures

Identifiers

PMID36064628
PMCPMC9446870
OpenAlexW4294647559

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.