Evidence map›Paper›PMID 36065499›Full record

ReviewAnatomical record (Hoboken, N.J. : 2007)2025

Impact of fetal treatments for congenital diaphragmatic hernia on lung development.

Mar Janna Dahl, Anna Lavizzari, Jonathan W Davis, Peter B Noble, Raffaele Dellacà, J Jane Pillow

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Anatomical record (Hoboken, N.J. : 2007), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mar Janna DahlSchool of Human Sciences, University of Western Australia, Perth, Western Australia, Australia.ORCID 0000-0002-3808-7995
Anna LavizzariNICU, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Jonathan W DavisMedical School, University of Western Australia, Perth, Western Australia, Australia.
Peter B NobleSchool of Human Sciences, University of Western Australia, Perth, Western Australia, Australia.
Raffaele DellacàDipartimento di Elettronica, Informazione e Bioingegneria, Politecnico di Milano University, Milan, Italy.
J Jane PillowSchool of Human Sciences, University of Western Australia, Perth, Western Australia, Australia.
The Kids Research Institute Australia · AUThe University of Western Australia · AUFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITPolitecnico di Milano · IT

Funding

Metropolitan Health Research Infrastructure FundNational Health and Medical Research Council 1196188Telethon Perth Children's Hospital Research Fund
6 · The paper itself

Abstract

The extent of lung hypoplasia impacts the survival and severity of morbidities associated with congenital diaphragmatic hernia (CDH). The alveoli of CDH infants and in experimental models of CDH have thickened septa with fewer type II pneumocytes and capillaries. Fetal treatments of CDH-risk preterm birth. Therefore, treatments must aim to balance the need for increased gas exchange surface area with the restoration of pulmonary epithelial type II cells and the long-term respiratory and neurodevelopmental consequences of prematurity. Achievement of sufficient lung development in utero for successful postnatal transition requires adequate intra-thoracic space for lung growth, maintenance of sufficient volume and appropriate composition of fetal lung fluid, regular fetal breathing movements, appropriate gas exchange area, and ample surfactant production. The review aims to examine the rationale for current and future therapeutic strategies to improve postnatal outcomes of infants with CDH.

Indexed as

Fetal TherapiesHernias, Diaphragmatic, CongenitalLungAnimalsHumansInfant, NewbornPregnancyalveolar developmentcongenital diaphragmatic herniafetal researchlung hypoplasia

Identifiers

PMID36065499
PMCPMC11889483
OpenAlexW4294751189

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.