ArticleEndocrinology and metabolism (Seoul, Korea)2022
Characteristics of Glycemic Control and Long-Term Complications in Patients with Young-Onset Type 2 Diabetes.
Article in Endocrinology and metabolism (Seoul, Korea), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 15 citations in OpenAlex.
- Semaglutide Treatment in Young Adults Living With Type 2 Diabetes: A Post Hoc Analysis From the SUSTAIN and PIONEER Clinical Trials.Diabetes, obesity & metabolism · 2026Trial
- Age-related patterns of cardiometabolic risk factors for complications in type 2 diabetes.Diabetologia · 2026Article
- Real-world effectiveness of quadruple oral hypoglycemic therapy in type 2 diabetes patients refusing insulin therapy.BMC endocrine disorders · 2026Article
- Differences in cardiovascular disease incidence according to changes in obesity status in young diabetic patients.Cardiovascular diabetology. Endocrinology reports · 2025Article
- Management of Early-Onset Type 2 Diabetes in Adults: Current Evidence and Future Directions.Diabetes & metabolism journal · 2025Review
- The Severity of Diabetes and the Risk of Diabetic Foot Amputation: A National Cohort Study.Endocrinology and metabolism (Seoul, Korea) · 2025Article
- Association between body mass index and survival after hematopoietic stem cell transplantation.The Korean journal of internal medicine · 2025Article
- Young patients with type 2 diabetes have high relative risks for complications in a country with middle-high sociodemographic index, similarly to those countries with high index.Frontiers in endocrinology · 2025Review
- Profiling of Macrovascular and Microvascular Complications in Young-Onset Type 2 Diabetes: A Scoping Review.Clinical diabetes : a publication of the American Diabetes Association · 2025Article
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- Early onset type 2 diabetes mellitus: an update.Endocrine · 2024Review
- Impact of diabetes distress on glycemic control and diabetic complications in type 2 diabetes mellitus.Scientific reports · 2024Article
- Younger-Onset Diabetes: Is the Age of Onset More Important than the Duration of Diabetes?Endocrinology and metabolism (Seoul, Korea) · 2024Article
- Long-Term Cumulative Exposure to High γ-Glutamyl Transferase Levels and the Risk of Cardiovascular Disease: A Nationwide Population-Based Cohort Study.Endocrinology and metabolism (Seoul, Korea) · 2023Article
- Complications and Treatment of Early-Onset Type 2 Diabetes.International journal of endocrinology and metabolism · 2023Review
- Characteristics of Glycemic Control and Long-Term Complications in Patients with Young-Onset Type 2 Diabetes (Endocrinol Metab 2022;37:641-51, Han-sang Baek et al.).Endocrinology and metabolism (Seoul, Korea) · 2022Article
- Characteristics of Glycemic Control and Long-Term Complications in Patients with Young-Onset Type 2 Diabetes (Endocrinol Metab 2022;37:641-51, Han-sang Baek et al.).Endocrinology and metabolism (Seoul, Korea) · 2022Article
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Authors and funding
10 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgruoundThe prevalence of young-onset diabetes (YOD) has been increasing worldwide. As the incidence of YOD increases, it is necessary to determine the characteristics of YOD and the factors that influence its development and associated complications.
methodsIn this retrospective study, we recruited patients who were diagnosed with type 2 diabetes mellitus between June 2001 and December 2021 at a tertiary hospital. The study population was categorized according to age: YOD (age <40 years), middle-age-onset diabetes (MOD, 40≤ age <65 years), and late-onset diabetes (LOD, age ≥65 years). We examined trends in glycemic control by analyzing fasting glucose levels during the first year in each age group. A Cox proportional-hazards model was used to determine the relative risk of developing complications according to glycemic control trends.
resultsThe fasting glucose level at the time of diagnosis was highest in the YOD group (YOD 149±65 mg/dL; MOD 143±54 mg/dL; and LOD 140±55 mg/dL; p=0.009). In the YOD group, glucose levels decreased at 3 months, but increased by 12 months. YOD patients and those with poor glycemic control in the first year were at a higher risk of developing complications, whereas the risk in patients with LOD was not statistically significant.
conclusionYOD patients had higher glucose levels at diagnosis, and their glycemic control was poorly maintained. As poor glycemic control can influence the development of complications, especially in young patients, intensive treatment is necessary for patients with YOD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.