Evidence map›Paper›PMID 36066868›Full record

ArticleChemical research in toxicology2022

Development of an Integrated Platform to Assess the Physicochemical and Toxicological Properties of Wood Combustion Particulate Matter.

Dilpreet Singh, Dereje Damte Tassew, Jordan Nelson, Marie-Cecile G Chalbot, Ilias G Kavouras, Philip Demokritou, Yohannes Tesfaigzi

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Characterization of woodsmoke generated in the air pollution exposure lab and comparison to diesel exhaust.Toxicological sciences : an official journal of the Society of Toxicology · 2026
    Article
  4. Article
  5. Article
  6. Article
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dilpreet SinghCenter for Nanotechnology and Nanotoxicology, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Avenue, Boston, Massachusetts 02115, United States.ORCID 0000-0003-2090-1693
Dereje Damte TassewPulmonary and Critical Care Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, United States.
Jordan NelsonDepartment of Environmental Health Sciences, University of Alabama at Birmingham, 1600 University Blvd, Birmingham, Alabama 35216, United States.
Marie-Cecile G ChalbotDepartment of Environmental Health Sciences, University of Alabama at Birmingham, 1600 University Blvd, Birmingham, Alabama 35216, United States.
Ilias G KavourasDepartment of Environmental, Occupational, and Geospatial Health Sciences, CUNY Graduate School of Public Health & Health Policy, 55 West 125th Street, New York, New York 10027, United States.
Philip DemokritouCenter for Nanotechnology and Nanotoxicology, Harvard T.H. Chan School of Public Health, Harvard University, 665 Huntington Avenue, Boston, Massachusetts 02115, United States.ORCID 0000-0002-2484-9143
Yohannes TesfaigziPulmonary and Critical Care Medicine, Brigham and Women's Hospital, 75 Francis Street, Boston, Massachusetts 02115, United States.

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
Resolution of Epithelial Cell Hyperplasia in AsthmaR01HL068111 · NHLBI · LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE · PI TESFAIGZI, YOHANNES · 2003 to 2021
$10.9M
Engineered Nanomaterial Synthesis, Characterization and Method Development Center for Nano-safety ResearchU24ES026946 · NIEHS · HARVARD SCHOOL OF PUBLIC HEALTH · PI DEMOKRITOU, PHILIP · 2016 to 2020
$3.8M
Wood Smoke and Chronic Mucous HypersecretionR01HL140839 · NHLBI · LOVELACE BIOMEDICAL & ENVIRONMENTAL RESEARCH INSTITUTE · PI TESFAIGZI, YOHANNES · 2018 to 2021
$2.8M
NHLBI NIH HHS R01 HL068111NHLBI NIH HHS R01 HL140839NIEHS NIH HHS P30 ES005022NIEHS NIH HHS U24 ES026946
6 · The paper itself

Abstract

Wood burning contributes to indoor and ambient particulate matter (PM) pollution and has been associated with increased morbidity and mortality. Here, we present an integrated methodology that allows to generate, sample, and characterize wood smoke derived from different moisture contents and representative combustion conditions using pine wood as a model. Flaming, smoldering, and incomplete combustion were assessed for low-moisture pine, whereas both low-moisture pine and high-moisture pine were investigated under flaming conditions. Real-time monitoring of carbon monoxide, volatile organic compounds, and aerosol number concentration/size in wood smoke was performed. The PM was size-fractionated, sampled, and characterized for elemental/organic carbon, organic functional groups, and inorganic elements. Bioactivity of PM was assessed by measuring the sterile alpha motif (SAM) pointed domain containing ETS (E-twenty-six) transcription factor (SPDEF) gene promoter activity in human embryonic kidney 293 (HEK-293T) cells, a biomarker for mucin gene expression. Findings showed that moisture content and combustion condition significantly affected the organic and inorganic elemental composition of PM

Indexed as

Air PollutantsParticulate MatterSmokeVolatile Organic CompoundsCarbohydratesCarbon MonoxideHumansMucinsSugar AlcoholsTranscription FactorsWoodAir PollutantsCarbohydratesCarbon MonoxideMucinsParticulate MatterSmokeSugar AlcoholsTranscription FactorsVolatile Organic Compounds

Identifiers

PMID36066868
PMCPMC9491341

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.