Evidence map›Paper›PMID 36069528›Full record

ArticleeLife2022

Computational modeling and quantitative physiology reveal central parameters for brassinosteroid-regulated early cell physiological processes linked to elongation growth of the

Ruth Großeholz, Friederike Wanke, Leander Rohr, Nina Glöckner, Luiselotte Rausch, Stefan Scholl, Emanuele Scacchi, Amelie-Jette Spazierer, Lana Shabala, Sergey Shabala and 3 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
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  5. Molecular tipping points in plant cell surface HQuantitative plant biology · 2025
    Review
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  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 5 countries.

Ruth Großeholz *Centre for Organismal Studies, Heidelberg University, Heidelberg, Germany.
Friederike Wanke *Center for Molecular Biology of Plants, University of Tubingen, Tübingen, Germany.
Leander RohrCenter for Molecular Biology of Plants, University of Tubingen, Tübingen, Germany.ORCID 0000-0003-4592-4197
Nina GlöcknerCenter for Molecular Biology of Plants, University of Tubingen, Tübingen, Germany.
Luiselotte RauschCenter for Molecular Biology of Plants, University of Tubingen, Tübingen, Germany.
Stefan SchollCentre for Organismal Studies, Heidelberg University, Heidelberg, Germany.
Emanuele ScacchiCenter for Molecular Biology of Plants, University of Tubingen, Tübingen, Germany.
Amelie-Jette SpaziererCenter for Molecular Biology of Plants, University of Tubingen, Tübingen, Germany.
Lana ShabalaTasmanian Institute for Agriculture, University of Tasmania, Hobart, Australia.
Sergey ShabalaTasmanian Institute for Agriculture, University of Tasmania, Hobart, Australia.
Karin SchumacherCentre for Organismal Studies, Heidelberg University, Heidelberg, Germany.ORCID 0000-0001-6484-8105
Ursula Kummer *Centre for Organismal Studies, Heidelberg University, Heidelberg, Germany.
Klaus Harter *Center for Molecular Biology of Plants, University of Tubingen, Tübingen, Germany.ORCID 0000-0002-2150-6970
University of Tübingen · DEHeidelberg University · DEUniversity of Tasmania · AUUniversità degli Studi della Tuscia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brassinosteroids (BR) are key hormonal regulators of plant development. However, whereas the individual components of BR perception and signaling are well characterized experimentally, the question of how they can act and whether they are sufficient to carry out the critical function of cellular elongation remains open. Here, we combined computational modeling with quantitative cell physiology to understand the dynamics of the plasma membrane (PM)-localized BR response pathway during the initiation of cellular responses in the epidermis of the

Indexed as

ArabidopsisArabidopsis ProteinsBrassinosteroidsComputer SimulationGene Expression Regulation, PlantPlant RootsPotassium ChannelsProton-Translocating ATPasesSignal TransductionArabidopsis ProteinsBrassinosteroidsPotassium ChannelsProton-Translocating ATPasesA. thalianabr/bri1 perceptionbri1 signalingcomputational biologycomputational modelingplant biologyplant cell physiologyreceptor complexessystems biologytheoretical biology

Identifiers

PMID36069528
PMCPMC9525061
OpenAlexW4294921611

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.