ReviewScience translational medicine2022
Advances toward transformative therapies for tendon diseases.
Review in Science translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Platelet-rich plasma and corticosteroid injection for tendinopathy: a systematic review and meta-analysis.BMC musculoskeletal disorders · 2025Pooled it
- Human Umbilical Cord-Derived Mesenchymal Stem Cells-Involved Strategies: Advancing Tendon Injuries Therapy Towards Clinical Translation.Stem cell reviews and reports · 2026Review
- Tendon healing in the era of regenerative medicine: literature review.Annals of translational medicine · 2026Review
- Stem cell approaches for tendon repair: delusion or insight.The Journal of physiology · 2025Review
- Biomimetic Scaffolds with Dual Gradients of Biological Effectors for Tendon-to-Bone Repair.Advanced healthcare materials · 2025Article
- Graft Treatment for Rotator Cuff Tendon-Bone Interface Augmentation: Status and Prospects-A Narrative Review.Clinics in orthopedic surgery · 2025Review
- A Narrative Review on the Double Pulley-Triple Row Technique for Large to Massive Rotator Cuff Repair.Clinics in orthopedic surgery · 2025Review
- Achilles tendinopathy.Nature reviews. Disease primers · 2025Review
- Fat Expansion Not Fat Infiltration of Muscle Post Rotator Cuff Tendon Tears of the Shoulder: Regenerative Engineering Implications.Regenerative engineering and translational medicine · 2025Article
- Transcriptome-Optimized Hydrogel Design of a Stem Cell Niche for Enhanced Tendon Regeneration.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Antifibrotic and Pro-regenerative Effects of SMAD3 siRNA and Collagen I mRNA-Loaded Lipid Nanoparticles in Human Tenocytes.ACS applied nano materials · 2024Article
- Development of a nanoparticle-based tendon-targeting drug delivery system to pharmacologically modulate tendon healing.Science advances · 2024Article
- Engineering an extracellular matrix-functionalized, load-bearing tendon substitute for effective repair of large-to-massive tendon defects.Bioactive materials · 2024Article
- Study of the Synergistic Immunomodulatory and Antifibrotic Effects of Dual-Loaded Budesonide and Serpine1 siRNA Lipid-Polymer Nanoparticles Targeting Macrophage Dysregulation in Tendinopathy.ACS applied materials & interfaces · 2024Article
- Antioxidant and anti-inflammatory injectable hydrogel microspheres forRegenerative biomaterials · 2024Article
- Bio-Enhanced Neoligaments Graft Bearing FE002 Primary Progenitor Tenocytes: Allogeneic Tissue Engineering & Surgical Proofs-of-Concept for Hand Ligament Regenerative Medicine.Pharmaceutics · 2023Article
- Breakthrough treatments for accelerated wound healing.Science advances · 2023Review
- Linguistic Analysis Identifies Emergent Biomaterial Fabrication Trends for Orthopaedic Applications.Advanced healthcare materials · 2023Review
- Process Optimization and Efficacy Assessment of Standardized PRP for Tendinopathies in Sports Medicine: Retrospective Study of Clinical Files and GMP Manufacturing Records in a Swiss University Hospital.Bioengineering (Basel, Switzerland) · 2023Article
- Applications of functionally-adapted hydrogels in tendon repair.Frontiers in bioengineering and biotechnology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
Approved therapies for tendon diseases have not yet changed the clinical practice of symptomatic pain treatment and physiotherapy. This review article summarizes advances in the development of novel drugs, biologic products, and biomaterial therapies for tendon diseases with perspectives for translation of integrated therapies. Shifting from targeting symptom relief toward disease modification and prevention of disease progression may open new avenues for therapies. Deep evidence-based clinical, cellular, and molecular characterization of the underlying pathology of tendon diseases, as well as therapeutic delivery optimization and establishment of multidiscipline interorganizational collaboration platforms, may accelerate the discovery and translation of transformative therapies for tendon diseases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.