Evidence map›Paper›PMID 36075865›Full record

ArticleMolecular informatics2022

Extensive Molecular Dynamics Simulations Disclosed the Stability of mPGES-1 Enzyme and the Structural Role of Glutathione (GSH) Cofactor.

Simone Di Micco, Gianluigi Lauro, Giuseppe Bifulco

Abstract read
In one paragraph

Article in Molecular informatics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Simone Di MiccoEuropean Biomedical Research Institute of Salerno (EBRIS), via Salvatore De Renzi 50, 84125, Salerno, Italy.
Gianluigi LauroDipartimento di Farmacia, University degli Studi di Salerno, via Giovanni Paolo II 132, 84084, Fisciano (SA), Italy.
Giuseppe BifulcoDipartimento di Farmacia, University degli Studi di Salerno, via Giovanni Paolo II 132, 84084, Fisciano (SA), Italy.ORCID 0000-0002-1788-5170

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A deep in silico investigation of various microsomal prostaglandin E

Indexed as

GlutathioneMolecular Dynamics SimulationGlutathionecancerinflammationMM-GBSAmolecular dynamicsmPGES-1

Identifiers

PMID36075865
PMCPMC10078397

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.