Evidence map›Paper›PMID 36077188›Full record

ArticleInternational journal of molecular sciences2022

Investigating the Expression and Function of the Glucose Transporter GLUT6 in Obesity.

Sing-Young Chen, Ellen M Olzomer, Martina Beretta, James Cantley, Craig S Nunemaker, Kyle L Hoehn, Frances L Byrne

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Sing-Young ChenSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0001-5258-8254
Ellen M OlzomerSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-5823-0736
Martina BerettaSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.
James CantleySchool of Medicine, University of Dundee, Dundee DD1 4HN, UK.
Craig S NunemakerHeritage College of Osteopathic Medicine, Ohio University, Athens, OH 45701, USA.
Kyle L HoehnSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-0214-3238
Frances L ByrneSchool of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia.ORCID 0000-0002-8897-8438
UNSW Sydney · AUOhio University · USUniversity of Dundee · GB

Funding

Cancer Institute of New South Wales 2021/CDF1120 (FLB)UNSW Sydney Scientia PhD Scholarship (SYC)
6 · The paper itself

Abstract

Obesity-related insulin resistance is a highly prevalent and growing health concern, which places stress on the pancreatic islets of Langerhans by increasing insulin secretion to lower blood glucose levels. The glucose transporters GLUT1 and GLUT3 play a key role in glucose-stimulated insulin secretion in human islets, while GLUT2 is the key isoform in rodent islets. However, it is unclear whether other glucose transporters also contribute to insulin secretion by pancreatic islets. Herein, we show that

Indexed as

Diabetes Mellitus, Type 2AnimalsGlucoseGlucose Transport Proteins, FacilitativeHumansInsulinIslets of LangerhansMiceMice, Inbred C57BLMice, KnockoutMice, ObeseObesityGlucoseGlucose Transport Proteins, FacilitativeInsulinSlc2a6 protein, mouseglucose transporterislet biologymouse modelobesity

Identifiers

PMID36077188
PMCPMC9456207
OpenAlexW4293724160

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.