Evidence map›Paper›PMID 36077603›Full record

ArticleCancers2022

Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions.

Anne Zaremba, Philipp Jansen, Rajmohan Murali, Anand Mayakonda, Anna Riedel, Dieter Krahl, Hans Burkhardt, Stefan John, Cyrill Géraud, Manuel Philip and 14 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 3 institutions in 2 countries.

Anne ZarembaDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Philipp JansenDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.ORCID 0000-0003-3139-2118
Rajmohan MuraliDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.
Anand MayakondaDivision of Cancer Epigenomics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Anna RiedelDivision of Cancer Epigenomics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Dieter KrahlInstitute for Dermatohistopathlogy, 69120 Heidelberg, Germany.
Hans BurkhardtDermatology, 66482 Zweibrücken, Germany.
Stefan JohnDermatology, 66346 Püttlingen, Germany.
Cyrill GéraudDepartment of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, Heidelberg University, 69117 Mannheim, Germany.
Manuel PhilipDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Julia KretzDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Inga MöllerDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Nadine StadtlerDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Antje SuckerDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Annette PaschenDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.ORCID 0000-0003-1651-1262
Selma UgurelDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.ORCID 0000-0002-9384-6704
Lisa ZimmerDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Elisabeth LivingstoneDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.ORCID 0000-0001-8279-9239
Susanne HornDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Christoph PlassDivision of Cancer Epigenomics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Dirk SchadendorfDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Eva HadaschikDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.
Pavlo LutsikDivision of Cancer Epigenomics, German Cancer Research Center (DKFZ), 69120 Heidelberg, Germany.
Klaus GriewankDepartment of Dermatology, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45122 Essen, Germany.ORCID 0000-0003-3899-9449
German Cancer Research Center · DEHeidelberg University · DEMemorial Sloan Kettering Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Deutsche Forschungsgemeinschaft HO 6389/2-2Deutsche Forschungsgemeinschaft PA 2376/1-2Deutsche Forschungsgemeinschaft SCHA 422/17-2NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

Melanocytic neoplasms have been genetically characterized in detail during the last decade. Recurrent

Indexed as

deep penetrating melanomadeep penetrating nevusimmune checkpoint inhibitionmalignant melanomamutation profiling

Identifiers

PMID36077603
PMCPMC9454999
OpenAlexW4293157127

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.