Evidence map›Paper›PMID 36077716›Full record

ArticleCancers2022

Detection and Characterization of Circulating Tumor Cells Using Imaging Flow Cytometry-A Perspective Study.

Anna Muchlińska, Julia Smentoch, Anna J Żaczek, Natalia Bednarz-Knoll

Abstract read
In one paragraph

Article in Cancers, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
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  11. Liquid biopsy techniques and lung cancer: diagnosis, monitoring and evaluation.Journal of experimental & clinical cancer research : CR · 2024
    Review
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  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna MuchlińskaLaboratory of Translational Oncology, Medical University of Gdańsk, 80-210 Gdańsk, Poland.ORCID 0000-0001-5886-4854
Julia SmentochLaboratory of Translational Oncology, Medical University of Gdańsk, 80-210 Gdańsk, Poland.ORCID 0000-0002-3410-089X
Anna J ŻaczekLaboratory of Translational Oncology, Medical University of Gdańsk, 80-210 Gdańsk, Poland.ORCID 0000-0003-1482-6068
Natalia Bednarz-KnollLaboratory of Translational Oncology, Medical University of Gdańsk, 80-210 Gdańsk, Poland.ORCID 0000-0001-9506-942X

Funding

National Centre for Research and Development WPC/33/HESCAP/2s018National Science Center 2017/26/D/NZ5/01088
6 · The paper itself

Abstract

Tumor dissemination is one of the most-investigated steps of tumor progression, which in recent decades led to the rapid development of liquid biopsy aiming to analyze circulating tumor cells (CTCs), extracellular vesicles (EVs), and circulating nucleic acids in order to precisely diagnose and monitor cancer patients. Flow cytometry was considered as a method to detect CTCs; however, due to the lack of verification of the investigated cells' identity, this method failed to reach clinical utility. Meanwhile, imaging flow cytometry combining the sensitivity and high throughput of flow cytometry and image-based detailed analysis through a high-resolution microscope might open a new avenue in CTC technologies and provide an open-platform system alternative to CellSearch

Indexed as

circulating tumor cellsimaging flow cytometryliquid biopsy

Identifiers

PMID36077716
PMCPMC9454939

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.