Evidence map›Paper›PMID 36077913›Full record

ReviewAnimals : an open access journal from MDPI2022

The Future of Biomarkers in Veterinary Medicine: Emerging Approaches and Associated Challenges.

Tharangani R W Perera, David A Skerrett-Byrne, Zamira Gibb, Brett Nixon, Aleona Swegen

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Animals : an open access journal from MDPI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Review
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  9. Article
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  11. Review
  12. Reference Intervals for Hematological Inflammatory Ratios in Healthy Dogs.Animals : an open access journal from MDPI · 2025
    Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Low-Invasive Biomarkers of Canine Mammary Tumours.Veterinary medicine and science · 2025
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tharangani R W PereraPriority Research Centre for Reproductive Science, College of Engineering, Science and Environment, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0003-1096-7955
David A Skerrett-ByrnePriority Research Centre for Reproductive Science, College of Engineering, Science and Environment, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0002-1804-1826
Zamira GibbPriority Research Centre for Reproductive Science, College of Engineering, Science and Environment, University of Newcastle, Callaghan, NSW 2308, Australia.
Brett NixonPriority Research Centre for Reproductive Science, College of Engineering, Science and Environment, University of Newcastle, Callaghan, NSW 2308, Australia.ORCID 0000-0003-2745-8188
Aleona SwegenPriority Research Centre for Reproductive Science, College of Engineering, Science and Environment, University of Newcastle, Callaghan, NSW 2308, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

New biomarkers promise to transform veterinary practice through rapid diagnosis of diseases, effective monitoring of animal health and improved welfare and production efficiency. However, the road from biomarker discovery to translation is not always straightforward. This review focuses on molecular biomarkers under development in the veterinary field, introduces the emerging technological approaches transforming this space and the role of 'omics platforms in novel biomarker discovery. The vast majority of veterinary biomarkers are at preliminary stages of development and not yet ready to be deployed into clinical translation. Hence, we examine the major challenges encountered in the process of biomarker development from discovery, through validation and translation to clinical practice, including the hurdles specific to veterinary practice and to each of the 'omics platforms-transcriptomics, proteomics, lipidomics and metabolomics. Finally, recommendations are made for the planning and execution of biomarker studies with a view to assisting the success of novel biomarkers in reaching their full potential.

Indexed as

biomarkersgenomicslipidomicsmetabolomicsproteomicstranscriptomicsveterinary

Identifiers

PMID36077913
PMCPMC9454634

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.