Evidence map›Paper›PMID 36078513›Full record

SynthesisInternational journal of environmental research and public health2022

Economic Evaluations of Magnetic Resonance Image-Guided Radiotherapy (MRIgRT): A Systematic Review.

Alessandra Castelluccia, Pierpaolo Mincarone, Maria Rosaria Tumolo, Saverio Sabina, Riccardo Colella, Antonella Bodini, Francesco Tramacere, Maurizio Portaluri, Carlo Giacomo Leo

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in International journal of environmental research and public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Health Economic Evaluation of Proton Therapy for Lung Cancer: A Systematic Review.International journal of environmental research and public health · 2023
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Alessandra CastellucciaRadiation Oncology, Department of Radiotherapy, Hospital "A. Perrino", ASL Brindisi, 72100 Brindisi, Italy.
Pierpaolo MincaroneInstitute for Research on Population and Social Policies, National Research Council, 72100 Brindisi, Italy.ORCID 0000-0002-8452-5642
Maria Rosaria TumoloDepartment of Biological and Environmental Sciences and Technology, University of Salento, 73100 Lecce, Italy.
Saverio SabinaMOVE-Mentis s.r.l., 47522 Cesena, Italy.ORCID 0000-0002-5337-2356
Riccardo ColellaDepartment of Engineering for Innovation, University of Salento, 73100 Lecce, Italy.
Antonella BodiniInstitute for Applied Mathematics and Information Technologies "E. Magenes", National Research Council, 20133 Milan, Italy.ORCID 0000-0002-3419-3184
Francesco TramacereRadiation Oncology, Department of Radiotherapy, Hospital "A. Perrino", ASL Brindisi, 72100 Brindisi, Italy.
Maurizio PortaluriRadiation Oncology, Department of Radiotherapy, Hospital "A. Perrino", ASL Brindisi, 72100 Brindisi, Italy.
Carlo Giacomo LeoMOVE-Mentis s.r.l., 47522 Cesena, Italy.ORCID 0000-0002-1357-4578
Ospedale A. Perrino · ITAzienda-Unita' Sanitaria Locale Di Cesena · ITUniversity of Salento · ITInstitute for Research on Population and Social Policies · ITNational Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis review systematically summarizes the evidence on the economic impact of magnetic resonance image-guided RT (MRIgRT).

methodsWe systematically searched INAHTA, MEDLINE, and Scopus up to March 2022 to retrieve health economic studies. Relevant data were extracted on study type, model inputs, modeling methods and economic results.

resultsFive studies were included. Two studies performed a full economic assessment to compare the cost-effectiveness of MRIgRT with other forms of image-guided radiation therapy. One study performed a cost minimization analysis and two studies performed an activity-based costing, all comparing MRIgRT with X-ray computed tomography image-guided radiation therapy (CTIgRT). Prostate cancer was the target condition in four studies and hepatocellular carcinoma in one. Considering the studies with a full economic assessment, MR-guided stereotactic body radiation therapy was found to be cost effective with respect to CTIgRT or conventional or moderate hypofractionated RT, even with a low reduction in toxicity. Conversely, a greater reduction in toxicity is required to compete with extreme hypofractionated RT without MR guidance.

conclusionsThis review highlights the great potential of MRIgRT but also the need for further evidence, especially for late toxicity, whose reduction is expected to be the real added value of this technology.

Indexed as

Radiotherapy, Image-GuidedCost-Benefit AnalysisHumansMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMaleTomography, X-Ray Computedadaptive radiation therapyeconomic evaluationimage-guided radiotherapyMRI-guided radiotherapysystematic review

Identifiers

PMID36078513
PMCPMC9517760
OpenAlexW4293776885

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.