Evidence map›Paper›PMID 36079720›Full record

ArticleNutrients2022

Intrahepatic Fat Content and COVID-19 Lockdown in Adults with NAFLD and Metabolic Syndrome.

Sofía Montemayor, Catalina M Mascaró, Lucía Ugarriza, Miguel Casares, Cristina Gómez, J Alfredo Martínez, Josep A Tur, Cristina Bouzas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. COVID-19 and Fatty Liver Disorders.Journal of clinical medicine · 2023
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Sofía MontemayorResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0001-7833-2118
Catalina M MascaróResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.
Lucía UgarrizaResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.
Miguel CasaresRadiodiagnosis Service, Red Asistencial Juaneda, 07011 Palma de Mallorca, Spain.
Cristina GómezResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0002-9776-4730
J Alfredo MartínezCenter for Nutrition Research, Department of Nutrition, Food Sciences, and Physiology, University of Navarra, 31008 Pamplona, Spain.
Josep A TurResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0002-6940-0761
Cristina BouzasResearch Group on Community Nutrition and Oxidative Stress, University of the Balearic Islands-IUNICS, 07122 Palma de Mallorca, Spain.ORCID 0000-0002-1407-8461
Health Research Institute of the Balearic Islands · ESInstituto de Salud Carlos III · ESMadrid Institute for Advanced Studies · ES

Funding

European Regional Development Fund N/AFundació La Marató TV3 201630.10IDISBA FOLIUM, PRIMUS, SYNERGIA, and LIBERIInstituto de Salud Carlos III CIBEROBN CB12/03/30038, and Proyecto Intramural CIBER OBN18PI03Spanish Agency of Research (MCINN) post-doctoral grant Juan de la CiervaSpanish Ministry of Education FPU PhD grant
6 · The paper itself

Abstract

backgroundCOVID-19 lockdowns had a significant impact on people's health, triggering levels of anxiety, perceived stress, and changes in food and nutritional status.

objectivesTo assess the changes in dietary habits, metabolic syndrome (MetS) and liver parameters before and after the COVID-19 lockdown according to changes in intrahepatic fat content in adults with non-alcoholic fatty liver disease (NAFLD) and MetS.

designPre- and post-lockdown observation of the COVID-19 lockdown on fifty-nine 40-60-year-old participants with MetS and NAFLD, in a parallel group, randomised experiment intended to treat NAFLD.

methodsAnthropometrics, liver and MetS biochemical parameters, intrahepatic fat content by abdominal magnetic resonance imaging, and dietary assessment using a validated 148-item Food Frequency Questionnaire were collected pre-COVID-19 lockdown and post-lockdown.

resultsCOVID-19 lockdown led to negative changes in the liver of patients with NAFLD and MetS, with weight gain and increases in glycemia, ALT and intrahepatic fat content post lockdown. Participants with worsened liver status had low consumption of fibre, cheese, nuts and coffee, and high consumption of sweets and pastries. Participants who improved liver status ameliorated ALT values, waist circumference, and intrahepatic fat content, assessed by magnetic resonance imaging post-lockdown.

conclusionsThe maintenance of healthy lifestyle habits is vital, especially for populations with NAFLD and MetS, to reduce unhealthy lifestyle patterns displayed during lockdown.

Indexed as

Body Fat DistributionCOVID-19LiverMetabolic SyndromeNon-alcoholic Fatty Liver DiseaseAdultCommunicable Disease ControlFeeding BehaviorHumansMagnetic Resonance ImagingMiddle AgedCOVID-19dietary habitsintrahepatic fat contentlockdownmetabolic syndromeNAFLD

Identifiers

PMID36079720
PMCPMC9457922
OpenAlexW4293220751

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.