Evidence map›Paper›PMID 36080219›Full record

ReviewMolecules (Basel, Switzerland)2022

Combination Anticancer Therapies Using Selected Phytochemicals.

Wamidh H Talib, Dima Awajan, Reem Ali Hamed, Aya O Azzam, Asma Ismail Mahmod, Intisar Hadi Al-Yasari

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  3. The logarithmic phase as a therapeutic direction: evaluating pharmacological strategies against cancer progression.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Wamidh H TalibDepartment of Clinical Pharmacy and Therapeutic, Applied Science Private University, Amman 11931-166, Jordan.ORCID 0000-0003-1942-8982
Dima AwajanDepartment of Clinical Pharmacy and Therapeutic, Applied Science Private University, Amman 11931-166, Jordan.ORCID 0000-0002-1300-3353
Reem Ali HamedDepartment of Clinical Pharmacy and Therapeutic, Applied Science Private University, Amman 11931-166, Jordan.
Aya O AzzamDepartment of Clinical Pharmacy and Therapeutic, Applied Science Private University, Amman 11931-166, Jordan.
Asma Ismail MahmodDepartment of Clinical Pharmacy and Therapeutic, Applied Science Private University, Amman 11931-166, Jordan.ORCID 0000-0002-4591-7408
Intisar Hadi Al-YasariDepartment of Genetic Engineering, College of Biotechnology, Al-Qasim Green University, Babylon 964, Iraq.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer is still one of the most widespread diseases globally, it is considered a vital health challenge worldwide and one of the main barriers to long life expectancy. Due to the potential toxicity and lack of selectivity of conventional chemotherapeutic agents, discovering alternative treatments is a top priority. Plant-derived natural products have high potential in cancer treatment due to their multiple mechanisms of action, diversity in structure, availability in nature, and relatively low toxicity. In this review, the anticancer mechanisms of the most common phytochemicals were analyzed. Furthermore, a detailed discussion of the anticancer effect of combinations consisting of natural product or natural products with chemotherapeutic drugs was provided. This review should provide a strong platform for researchers and clinicians to improve basic and clinical research in the development of alternative anticancer medicines.

Indexed as

Antineoplastic AgentsBiological ProductsNeoplasmsHumansPhytochemicalsAntineoplastic AgentsBiological ProductsPhytochemicalsalternative anticancer therapycancercurcuminnatural productsresveratrol

Identifiers

PMID36080219
PMCPMC9458090

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.