Evidence map›Paper›PMID 36080256›Full record

ArticleMolecules (Basel, Switzerland)2022

The Effect of a New

Denis A Borozdenko, Tatiana A Shmigol, Aiarpi A Ezdoglian, Darya I Gonchar, Natalia Y Karpechenko, Dmitri N Lyakhmun, Anastasia D Shagina, Elvira A Cherkashova, Daria D Namestnikova, Ilya L Gubskiy and 4 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Denis A BorozdenkoDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-6797-9722
Tatiana A ShmigolDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-5195-0845
Aiarpi A EzdoglianDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-4599-2053
Darya I GoncharDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0003-3327-692X
Natalia Y KarpechenkoDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-5902-0378
Dmitri N LyakhmunDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0002-0760-0899
Anastasia D ShaginaDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.
Elvira A CherkashovaDepartment of Medical Nanobiotechnologies, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0001-9549-9104
Daria D NamestnikovaDepartment of Medical Nanobiotechnologies, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0001-6635-511X
Ilya L GubskiyDepartment of Medical Nanobiotechnologies, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0003-1726-6801
Anastasia A ChernyshevaSerbsky National Medical Research Center for Psychiatry and Narcology, 119034 Moscow, Russia.ORCID 0000-0002-9793-0129
Nina M KiselevaDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0003-1754-9051
Vadim V NegrebetskyDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.ORCID 0000-0001-6852-8942
Yuri I BaukovDepartment of Medicinal Chemistry and Toxicology, Pirogov National Research Medical University, Ministry of Health of Russia, 117997 Moscow, Russia.
Pirogov Russian National Research Medical University · RUFederal Medical Research Centre for Psychiatry and Narcology · RU

Funding

the Russian Foundation of Basic Research 20-03-00858the Russian Science Foundation 21-73-20250
6 · The paper itself

Abstract

Ischemic stroke triggers a whole cascade of pathological changes in the brain, one of which is postischemic inflammation. Since in such cases thrombolytic therapy is often not possible, methods that modulate inflammation and affect microglia become particularly interesting. We synthesized 3-(2-oxo-4-phenylpyrrolidin-1-yl)propane-1-sulfonate calcium(II) (Compound

Indexed as

Brain IschemiaIschemic StrokeNeuroprotective AgentsStrokeAnimalsAnti-Inflammatory AgentsCytokinesDisease Models, AnimalInfarction, Middle Cerebral ArteryInflammationMicrogliaRatsAnti-Inflammatory AgentsCytokinesNeuroprotective Agentsbehavioral testsexperimental ischemic strokeinflammationneuroprotective activitytransient MCAO

Identifiers

PMID36080256
PMCPMC9457934
OpenAlexW4293761036

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.