Evidence map›Paper›PMID 36080269›Full record

ReviewMolecules (Basel, Switzerland)2022

Unveiling Natural and Semisynthetic Acylated Flavonoids: Chemistry and Biological Actions in the Context of Molecular Docking.

Dina M El-Kersh, Rania F Abou El-Ezz, Marwa Fouad, Mohamed A Farag

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. The inhibitory activities of two compounds fromPlant signaling & behavior · 2025
    Article
  3. Article
  4. Article
  5. Enzymatic hydrolysis of ∆Forensic toxicology · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. How DoesFoods (Basel, Switzerland) · 2023
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dina M El-KershDepartment of Pharmacognosy, Faculty of Pharmacy, The British University in Egypt (BUE), Cairo 11837, Egypt.ORCID 0000-0002-4782-8396
Rania F Abou El-EzzPharmacognosy Department, Faculty of Pharmacy, Misr International University, Cairo, Egypt.
Marwa FouadPharmaceutical Chemistry Department, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt.ORCID 0000-0003-3227-8683
Mohamed A FaragPharmacognosy Department, College of Pharmacy, Cairo University, Kasr El Aini St., Cairo 11652, Egypt.ORCID 0000-0001-5139-1863

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acylated flavonoids are widely distributed natural metabolites in medicinal plants and foods with several health attributes. A large diversity of chemical structures of acylated flavonoids with interesting biological effects was reported from several plant species. Of these, 123 compounds with potential antimicrobial, antiparasitic, anti-inflammatory, anti-nociceptive, analgesic, and anti-complementary effects were selected from several databases including SCI-Finder, Scopus, Google Scholar, Science Direct, PubMed, and others. Some selected reported biologically active flavonoids were docked in the active binding sites of some natural enzymes, namely acetylcholinesterase, butyrylcholinesterase, α-amylase, α-glucosidase, aldose reductase, and HIV integrase, in an attempt to underline the key interactions that might be responsible for their biological activities.

Indexed as

ButyrylcholinesteraseFlavonoidsAcetylcholinesterasealpha-GlucosidasesMolecular Docking SimulationPlant ExtractsAcetylcholinesterasealpha-GlucosidasesButyrylcholinesteraseFlavonoidsPlant Extractsacetylcholinesteraseacylated flavonoidsanti-diabetichepatoprotectivemedicinal plants

Identifiers

PMID36080269
PMCPMC9458193

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.