Evidence map›Paper›PMID 36080389›Full record

ArticleMolecules (Basel, Switzerland)2022

Effects of Extraction Technique on the Content and Antioxidant Activity of Flavonoids from Gossypium

Jiaxing Dong, Kehai Zhou, Xiaoyang Ge, Na Xu, Xiao Wang, Qing He, Chenxu Zhang, Jun Chu, Qinglin Li

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Extraction and Purification of Flavonoids fromMolecules (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Jiaxing DongKey Laboratory of Xi'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei 230038, China.
Kehai ZhouState Key Laboratory of Cotton Biology, Institute of Cotton Research, Chinese Academy of Agriculture Sciences (CAAS), Anyang 455000, China.
Xiaoyang GeState Key Laboratory of Cotton Biology, Institute of Cotton Research, Chinese Academy of Agriculture Sciences (CAAS), Anyang 455000, China.
Na XuState Key Laboratory of Tea Plant Biology and Utilization, School of Tea & Food Science and International Joint Laboratory on Tea Chemistry and Health Effects of Ministry of Education, Anhui Agricultural University, Hefei 230036, China.
Xiao WangKey Laboratory of Xi'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei 230038, China.
Qing HeKey Laboratory of Xi'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei 230038, China.
Chenxu ZhangKey Laboratory of Xi'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei 230038, China.
Jun ChuKey Laboratory of Xi'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei 230038, China.
Qinglin LiKey Laboratory of Xi'an Medicine, Ministry of Education, Anhui University of Chinese Medicine, Hefei 230038, China.ORCID 0000-0001-9785-3875
Anhui University of Traditional Chinese Medicine · CNCotton Research Institute · CNAnhui Agricultural University · CN

Funding

Anhui Province Colleges and Universities Outstanding Talents Cultivation Overseas Visiting Program gxgwfx2019027Anhui Provincial Department of Education 2020 Key Project of Natural Science in Colleges and Universities RZ2000001209the Natural Science Foundation of Anhui Province 1808085MC71The Open Fund of State Key Laboratory of Tea Plant Biology and Utilization SKLTOF20210101
6 · The paper itself

Abstract

Cotton is one of the Uyghur medical materials in China and is rich in flavonoids. Flavonoids have important pharmacological effects. The yield of flavonoids in traditional extraction methods is low, which affects the development of flavonoids. Therefore, it is urgent to optimize the extraction techniques. The yield of flavonoids in cotton flowers was effectively improved by response surface methodology, and the highest yield of flavonoids reached 5.66%, and the optimal extraction process conditions were obtained. The DPPH free radical scavenging rate, hydroxyl free radical scavenging rate, superoxide anion free radical scavenging rate, and reducing ability were tested to reflect the antioxidant capacity of flavonoids. The flavonoids had an excellent antioxidant effect. Cell experiments suggested that the flavonoids had the effect of protecting glutamate-induced damage to HT-22 cells. The results of this study provide a theoretical basis for the extraction of cotton flowers flavonoids and the comprehensive evaluation of antioxidant products, as well as the extraction of other plant flavonoids.

Indexed as

AntioxidantsFlavonoidsFlowersFree RadicalsGossypiumPlant ExtractsAntioxidantsFlavonoidsFree RadicalsPlant Extractsantioxidant activitycotton flowers flavonoidsextraction processresponse surface methodology

Identifiers

PMID36080389
PMCPMC9458133
OpenAlexW4294292993

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.