Evidence mapPaperPMID 36080397Full record

ReviewMolecules (Basel, Switzerland)2022

Mechanism of Citri Reticulatae Pericarpium as an Anticancer Agent from the Perspective of Flavonoids: A Review.

Li Song, Peiyu Xiong, Wei Zhang, Hengchang Hu, Songqi Tang, Bo Jia, Wei Huang

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Li SongCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China.
Peiyu XiongCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China.
Wei ZhangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China.
Hengchang HuCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China.
Songqi TangCollege of Traditional Chinese Medicine, Hainan Medical University, Haikou 571199, China.ORCID 0000-0001-8314-4613
Bo JiaCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China.
Wei HuangCollege of Basic Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu 610000, China.
Chengdu University of Traditional Chinese Medicine · CNHainan Medical University · CN

Funding

National Natural Science Foundation Of China No.81860816
6 · The paper itself

Abstract

Citri Reticulatae Pericarpium (CRP), also known as "chenpi", is the most common qi-regulating drug in traditional Chinese medicine. It is often used to treat cough and indigestion, but in recent years, it has been found to have multi-faceted anti-cancer effects. This article reviews the pharmacology of CRP and the mechanism of the action of flavonoids, the key components of CRP, against cancers including breast cancer, lung cancer, prostate cancer, hepatic carcinoma, gastric cancer, colorectal cancer, esophageal cancer, cervical cancer, bladder cancer and other cancers with a high diagnosis rate. Finally, the specific roles of CRP in important phenotypes such as cell proliferation, apoptosis, autophagy and migration-invasion in cancer were analyzed, and the possible prospects and deficiencies of CRP as an anticancer agent were evaluated.

Indexed as

Antineoplastic AgentsCitrusDrugs, Chinese HerbalFlavonoidsMedicine, Chinese TraditionalAntineoplastic AgentsDrugs, Chinese HerbalFlavonoidsanticancerCitri Reticulatae Pericarpiumflavonoidsmechanismphenotype

Identifiers

PMID36080397
PMCPMC9458152
OpenAlexW4294162985

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.