Evidence mapPaperPMID 36082075Full record

SynthesisFrontiers in endocrinology2022

Abdominal Visceral Adipose Tissue and All-Cause Mortality: A Systematic Review.

Randa K Saad, Malak Ghezzawi, Renee Horanieh, Assem M Khamis, Katherine H Saunders, John A Batsis, Marlene Chakhtoura

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Randa K SaadCalcium Metabolism and Osteoporosis Program, World Health Organization (WHO) Collaborating Center for Metabolic Bone Disorders, Division of Endocrinology and Metabolism, Department of Internal Medicine - American University of Beirut Medical Center, Beirut, Lebanon.
Malak GhezzawiDepartement of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Renee HoraniehDepartement of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon.
Assem M KhamisWolfson Palliative Care Research Centre, Hull York Medical School, University of Hull, Hull, United Kingdom.
Katherine H SaundersDivision of Endocrinology, Diabetes & Metabolism, Weill Cornell Medicine, New York, NY, United States.
John A BatsisDivision of Geriatric Medicine and Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.
Marlene ChakhtouraCalcium Metabolism and Osteoporosis Program, World Health Organization (WHO) Collaborating Center for Metabolic Bone Disorders, Division of Endocrinology and Metabolism, Department of Internal Medicine - American University of Beirut Medical Center, Beirut, Lebanon.
American University of Beirut Medical Center · LBCornell University · USHull York Medical School · GBUniversity of North Carolina at Chapel Hill · US

Funding

FIC NIH HHS D43 TW009118
6 · The paper itself

Abstract

Introduction: Increased abdominal visceral adipose tissue (VAT) implies an adverse cardio-metabolic profile. We examined the association of abdominal VAT parameters and all-cause mortality risk. Methods: We systematically searched four databases. We performed citations/articles screening, data abstraction, and quality assessment in duplicate and independently (CRD42020205021). Results: We included 12 cohorts, the majority used computed tomography to assess abdominal VAT area. Six cohorts with a mean age ≤ 65 years, examining all-cause mortality risk per increment in VAT area (cm Conclusion: A high abdominal VAT area seems to be associated with increased all-cause mortality in individuals ≤ 65 years, possibly mediated by metabolic complications, and not through an independent effect. This relationship is weaker and may reverse in older individuals, most likely secondary to confounding bias and reverse causality. An individual participant data meta-analysis is needed to confirm our findings, and to define an abdominal VAT area cutoff implying increased mortality risk. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=205021, identifier CRD42020205021.

Indexed as

Abdominal FatIntra-Abdominal FatAgedBody Mass IndexHumansRisk FactorsTomography, X-Ray Computedabdominal visceral fatall-cause mortalityfatal outcomesystematic reviewvisceral adipose tissue

Identifiers

PMID36082075
PMCPMC9446237
OpenAlexW4292708153

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.