Evidence map›Paper›PMID 36082262›Full record

ArticleEuropean stroke journal2022

Lobar intracerebral hemorrhage and risk of subsequent uncontrolled blood pressure.

Evangelos Pavlos Myserlis, Ernst Mayerhofer, Jessica R Abramson, Kay-Cheong Teo, Bailey E Montgomery, Lansing Sugita, Andrew D Warren, Joshua N Goldstein, Mahmut Edip Gurol, Anand Viswanathan and 4 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European stroke journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Evangelos Pavlos MyserlisCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Ernst MayerhoferCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0001-8902-4209
Jessica R AbramsonCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Kay-Cheong TeoDepartment of Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, HK, China SAR.ORCID https://orcid.org/0000-0002-3291-2958
Bailey E MontgomeryCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Lansing SugitaCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Andrew D WarrenDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Joshua N GoldsteinDepartment of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.
Mahmut Edip GurolDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Anand ViswanathanDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Steven M GreenbergDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Alessandro BiffiDepartment of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
Christopher D AndersonCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Jonathan RosandCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.ORCID https://orcid.org/0000-0002-1014-9138
Broad Institute · USHarvard University · USMassachusetts General Hospital · USQueen Mary Hospital · CN

Funding

Ethnic/Racial Variation in Intracerebral Hemorrhage (ERICH)U01NS069763 · NINDS · UNIVERSITY OF CINCINNATI · PI ANDERSON, CHRISTOPHER DAVID, DEMEL, STACIE · 2010 to 2024
$34.2M
Recurrent Hemorrhagic Stroke in Minority PopulationsR01NS093870 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI JONATHAN ROSAND, Amytis Towfighi · 2016 to 2026
$12.3M
Sequencing Annotation and Functional Analysis in Risk of Intracerebral HemorrhageR01NS103924 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ANDERSON, CHRISTOPHER DAVID · 2018 to 2022
$3.4M
Apathy and Depression following Intracerebral HemorrhageK23NS100816 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BIFFI, ALESSANDRO · 2017 to 2021
$1.0M
NINDS NIH HHS K23 NS100816NINDS NIH HHS R01 NS093870NINDS NIH HHS R01 NS103924NINDS NIH HHS U01 NS069763
6 · The paper itself

Abstract

Background: Uncontrolled blood pressure (BP) in intracerebral hemorrhage (ICH) survivors is common and associated with adverse clinical outcomes. We investigated whether characteristics of the ICH itself were associated with uncontrolled BP at follow-up. Methods: Subjects were consecutive patients aged ⩾18 years with primary ICH enrolled in the prospective longitudinal ICH study at Massachusetts General Hospital between 1994 and 2015. We assessed the prevalence of uncontrolled BP (mean BP ⩾140/90 mmHg) 6 months after index event. We used multivariable logistic regression models to assess the effect of hematoma location, volume, and event year on uncontrolled BP. Results: Among 1492 survivors, ICH was lobar in 624 (42%), deep in 749 (50%), cerebellar in 119 (8%). Lobar ICH location was associated with increased risk for uncontrolled BP after 6 months (OR 1.35; 95% CI [1.08-1.69]). On average, lobar ICH survivors were treated with fewer antihypertensive drugs compared to the rest of the cohort: 2.1 ± 1.1 vs 2.5 ± 1.2 ( Conclusions: ICH survivors with lobar hemorrhage were more likely to have uncontrolled BP after 6 months follow-up. This appears to be a result of being prescribed fewer antihypertensive medications. Future treatment strategies should focus on aggressive BP control after ICH independent of hemorrhage location.

Indexed as

Blood pressureHypertensionIntracerebral hemorrhageStroke

Identifiers

PMID36082262
PMCPMC9446337
OpenAlexW4224930271

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.