Evidence map›Paper›PMID 36084848›Full record

SynthesisNeuroscience and biobehavioral reviews2022

Treatment of eating disorders: A systematic meta-review of meta-analyses and network meta-analyses.

Alessio Maria Monteleone, Francesca Pellegrino, Giovanni Croatto, Marco Carfagno, Anja Hilbert, Janet Treasure, Tracey Wade, Cynthia M Bulik, Stephan Zipfel, Phillipa Hay and 15 more

Open access · greenAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neuroscience and biobehavioral reviews, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 133 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
133citing papers in PubMed, 11 pooled it
45.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

133 citing papers in PubMed, 11 syntheses or guidelines pooled it, 259 citations in OpenAlex.

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  3. Emotion-Related Treatments in Patients With Binge Eating Episodes-a Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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73 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors at 11 institutions in 7 countries.

Alessio Maria MonteleoneDepartment of Psychiatry, University of Campania L. Vanvitelli, Naples, Italy. Electronic address: alessiomaria.monteleone@unicampania.it.
Francesca PellegrinoDepartment of Psychiatry, University of Campania L. Vanvitelli, Naples, Italy.
Giovanni CroattoNeurosciences Department, University of Padua, Padua, Italy.
Marco CarfagnoDepartment of Psychiatry, University of Campania L. Vanvitelli, Naples, Italy.
Anja HilbertIntegrated Research and Treatment Center AdiposityDiseases, Behavioral Medicine Research Unit, Department of Psychosomatic Medicine and Psychotherapy, University of Leipzig Medical Center, Leipzig, Germany.
Janet TreasureKing's College London, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Tracey WadeFlinders Institute for Mental Health and Well-Being, the Blackbird Initiative, Flinders University, South Australia, Australia.
Cynthia M BulikDepartment of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, USA; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, USA.
Stephan ZipfelDepartment of Psychosomatic Medicine and Psychotherapy, University Medical Hospital, Tuebingen, Germany; Centre of Excellence for Eating Disorders Tuebingen (KOMET), Germany.
Phillipa HayTranslational Health Research Institute, School of Medicine, Western Sydney University, Australia.
Ulrike SchmidtKing's College London, Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, London, UK.
Giovanni CastelliniPsychiatry Unit, Department of Health Sciences, University of Florence, Florence, Italy.
Angela FavaroNeurosciences Department, University of Padua, Padua, Italy.
Fernando Fernandez-ArandaDepartment of Psychiatry, Bellvitge University Hospital-IDIBELL and CIBERobn, ISCIII, Barcelona, Spain.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Republic of Korea.
Ulrich VoderholzerSchoen Clinic Roseneck, Prien am Chiemsee, Germany; Clinic for Psychiatry and Psychotherapy, University Hospital Freiburg, Freiburg, Germany; Clinic for Psychiatry and Psychotherapy, University Hospital of Munich, Munich, Germany.
Valdo RiccaPsychiatry Unit, Department of Health Sciences, University of Florence, Florence, Italy.
Davide MorettiPsychiatry Unit, Department of Health Sciences, University of Florence, Florence, Italy.
Daniele BusattaPsychiatry Unit, Department of Health Sciences, University of Florence, Florence, Italy.
Giovanni Abbate-DagaEating Disorders Center for Treatment and Research, Department of Neuroscience, University of Turin, Turin, Italy.
Filippo CiulliniDepartment of General Psychology, University of Padova, Padova, Italy.
Giammarco CascinoDepartment of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', Section of Neurosciences, University of Salerno, Salerno, Italy.
Francesco MonacoDepartment of Mental Health, Asl Salerno, Salerno, Italy.
Christoph U CorrellDepartment of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY, USA; Department of Psychiatry and Molecular Medicine, Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY, USA; Center for Psychiatric Neuroscience, Feinstein Institute for Medical Research, Manhasset, NY, USA; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.
Marco SolmiDepartment of Psychiatry, University of Ottawa, Ottawa, Ontario, Canada; Department of Mental Health, The Ottawa Hospital, Ottawa, Ontario, Canada; Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada; Department of Child and Adolescent Psychiatry, Charité Universitätsmedizin, Berlin, Germany.
University of Florence · ITUniversity of Padua · ITKing's College London · GBUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Salerno · ITIFB Adiposity Diseases · DEInstituto de Salud Carlos III · ESUniversity of North Carolina at Chapel Hill · USUniversity of Turin · ITWestern Sydney University · AUYonsei University · KR

Funding

Eating Disorders Genetics Initiative (EDGI)R01MH120170 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M · 2019 to 2023
$7.2M
Predicting the multi-omic impact of psychiatric GWAS associationsR01MH118278 · NIMH · YALE UNIVERSITY · PI HUCKINS, LAURA MARIANNE · 2019 to 2023
$3.6M
1/7 PGC: Advancing Discovery and ImpactR01MH124871 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, SULLIVAN, PATRICK F · 2021 to 2025
$3.5M
Predicting Binge and Purge Episodes from Passive and Active Apple Watch Data Using a Dynamical Systems ApproachR01MH119084 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BULIK, CYNTHIA M, BUTNER, JONATHAN · 2019 to 2022
$2.8M
Department of HealthNIMH NIH HHS R01 MH118278NIMH NIH HHS R01 MH119084NIMH NIH HHS R01 MH120170NIMH NIH HHS R01 MH124871
6 · The paper itself

Abstract

MONTELEONE, A.M., F. Pellegrino, G. Croatto, M. Carfagno, A. Hilbert, J. Treasure, T. Wade, C. Bulik, S. Zipfel, P. Hay, U. Schmidt, G. Castellini, A. Favaro, F. Fernandez-Aranda, J. Il Shin, U. Voderholzer, V. Ricca, D. Moretti, D. Busatta, G. Abbate-Daga, F. Ciullini, G. Cascino, F. Monaco, C.U. Correll and M. Solmi. Treatment of Eating Disorders: a systematic meta-review of meta-analyses and network meta-analyses. NEUROSCI BIOBEHAV REV 21(1) XXX-XXX, 2022.- Treatment efficacy for eating disorders (EDs) is modest and guidelines differ. We summarized findings/quality of (network) meta-analyses (N)MA of randomized controlled trials (RCTs) in EDs. Systematic meta-review ((N)MA of RCTs, ED, active/inactive control), using (anorexia or bulimia or eating disorder) AND (meta-analy*) in PubMed/PsycINFO/Cochrane database up to December 15th, 2020. Standardized mean difference, odds/risk ratio vs control were summarized at end of treatment and follow-up. Interventions involving family (family-based therapy, FBT) outperformed active control in adults/adolescents with anorexia nervosa (AN), and in adolescents with bulimia nervosa (BN). In adults with BN, individual cognitive behavioural therapy (CBT)-ED had the broadest efficacy versus active control; also, antidepressants outperformed active. In mixed age groups with binge-eating disorder (BED), psychotherapy, and lisdexamfetamine outperformed active control. Antidepressants, stimulants outperformed placebo, despite lower acceptability, as did CBT-ED versus waitlist/no treatment. Family-based therapy is effective in AN and BN (adolescents). CBT-ED has the largest efficacy in BN (adults), followed by antidepressants, as well as psychotherapy in BED (mixed). Medications have short-term efficacy in BED (adults).

Indexed as

Binge-Eating DisorderBulimiaBulimia NervosaFeeding and Eating DisordersAdolescentAdultAntidepressive AgentsHumansNetwork Meta-Analysis as TopicAntidepressive AgentsEating disordersPsychopharmacologyPsychotherapyRandomized controlled trialsTreatmentUmbrella review

Identifiers

PMID36084848
PMCPMC9813802
OpenAlexW4294770567

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.