Evidence map›Paper›PMID 36090704›Full record

ArticleInternational journal of general medicine2022

SARS-CoV-2 Seroepidemiological Investigation in Jordan: Seroprevalence, Herd Immunity, and Vaccination Coverage. A Population-Based National Study.

Sami Sheikh Ali, Khalid A Kheirallah, Ghazi Sharkas, Mohammed Al-Nusair, Abdel-Hameed Al-Mistarehi, Mahmoud Ghazo, Ali Zeitawi, Saverio Bellizzi, Mohannad Ramadan, Jomana W Alsulaiman and 3 more

Abstract read
In one paragraph

Article in International journal of general medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. COVID-19 Vaccines in the Pediatric Population: A Focus on Cardiac Patients.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sami Sheikh AliEpidemics Management, Jordan Ministry of Health, Amman, Jordan.
Khalid A KheirallahDepartment of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-4504-4472
Ghazi SharkasEpidemics Management, Jordan Ministry of Health, Amman, Jordan.
Mohammed Al-NusairDepartment of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-0572-780X
Abdel-Hameed Al-MistarehiDepartment of Public Health and Community Medicine, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-4713-8536
Mahmoud GhazoEpidemics Management, Jordan Ministry of Health, Amman, Jordan.
Ali ZeitawiEpidemics Management, Jordan Ministry of Health, Amman, Jordan.
Saverio BellizziEmergency Program, World Health Organization, Jordan Country Office, Amman, Jordan.
Mohannad RamadanEmergency Program, World Health Organization, Jordan Country Office, Amman, Jordan.
Jomana W AlsulaimanDepartment of Pediatrics, Faculty of Medicine, Yarmouk University, Irbid, Jordan.
Hamed AlzoubiDepartment of Microbiology and Immunology, Faculty of Medicine, Mutah University, Mutah, Jordan.
Adel BelbesiEpidemics Management, Jordan Ministry of Health, Amman, Jordan.
Mohammed Z AllouhDepartment of Anatomy, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.ORCID 0000-0003-0105-6260

Funding

World Health Organization 001
6 · The paper itself

Abstract

Background: Population-based serosurveillance is a cornerstone to furthering our understanding of the COVID-19 pandemic at the community levels. In Jordan, four waves (phases) of seroprevalence epidemiological investigations were conducted using representative population-based national samples. This study aims to estimate the population-based seropositivity, herd immunity, and vaccination coverage at the fourth wave. Methods: Multistage sampling technique was implemented to recruit a nationally representative sample for the fourth wave of the seroprevalence investigation (June to August 2021). Electronically collected data utilized a questionnaire on background demographics, chronic diseases, and COVID-19 vaccination history. Also, blood samples were collected to detect the presence of total Anti-SARS-CoV-2 IgM and IgG using Wantai/ELISA assays. Prevalence estimates were presented using percentage and 95% Confidence Intervals (C.I.). Results: There were 8821 participants included in this study, with a mean age of 31.3 years, and 61.7% were females. COVID-19 national seroprevalence and vaccination coverage estimates were 74.1% (95% C.I.: 73.1-74.9%) and 38.4% (95% C.I.: 37.1-39.6%), respectively. Among children, seroprevalence estimates were similar to unvaccinated adults. Among COVID-19 adults, 57.2% were vaccinated. Among vaccinated participants, 91.5% were seropositive, while among unvaccinated, 63.2% were seropositive. By age group, seroprevalence ranged between 53.0% and 86.9%. Seroprevalence estimates were significantly different by gender, vaccination status and dose, and residence. Conclusion: The reported interplay between seropositivity and vaccination coverage estimate seems insufficient to provide herd immunity levels to combat new variants of SARS-CoV-2. Children and healthcare workers seem to be an epidemiologically influential group in spreading COVID-19. As the globe is still grappling with SARS-CoV-2 infection, national seroepidemiological evidence from Jordan calls for more focus on vaccination coverage, especially among epidemiologically vulnerable groups, to optimize herd immunity.

Indexed as

COVID-19herd immunityJordanMiddle EastSARS-CoV-2seropositivityseroprevalencevaccination

Identifiers

PMID36090704
PMCPMC9462546

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.