ArticleFrontiers in public health2022
Gender disparity and temporal trend of liver cancer in China from 1990 to 2019 and predictions in a 25-year period.
Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 22 citations in OpenAlex.
- Latent profiles of self-advocacy and their relationship with fear of progression, family resilience, and cognitive emotion regulation among male patients with liver cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Global and regional burden of liver cancer attributable to drug use in elderly patients: a 1990-2021 analysis from the GBD study.Frontiers in oncology · 2026Article
- Novel role of general transcript factor IIH subunit 2 (GTF2H2) in the development and sex disparity of hepatocellular carcinoma.Oncogene · 2025Article
- Global, regional and national burden of liver cancer 1990-2021: a systematic analysis of the global burden of disease study 2021.BMC public health · 2025Article
- Temporal Trends in the Burden of Diabetes and Its Risk Factors Across the Western Pacific Region Between 1990 and 2044: A Systematic Analysis of the Global Burden of Disease Study 2019.Diabetes/metabolism research and reviews · 2025Article
- Comparative analysis of liver cancer burden trends in China and worldwide between 1990 and 2021.Frontiers in public health · 2025Article
- Burden of liver cancer resulting from different etiologies in China from 1990 to 2021 and prediction to 2031.PloS one · 2025Article
- Metabolic risks remain a serious threat to cardiovascular disease: findings from the Global Burden of Disease Study 2019.Internal and emergency medicine · 2024Article
- Global, regional and national burdens of Nasopharynx cancer in the adolescents and young adults from 1990 to 2019 and its predictions.BMC cancer · 2024Article
- Increasing Burden of Osteoarthritis in China: Trends and Projections from the Global Burden of Disease Study 2019.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
- Long-term trends in incidence, mortality and burden of liver cancer due to specific etiologies in Hubei Province.Scientific reports · 2024Article
- Asian Burden of Liver Cancer 1990-2021 and Predictions to 2040: An Analysis of the Global Burden of Disease Study 2021.Cancer control : journal of the Moffitt Cancer CenterArticle
- Diet Habits, Smoking, and Alcohol Consumption Among Chinese Patients with Cancer.Integrative cancer therapiesArticle
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Authors and funding
7 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: This study aims to reveal epidemiological features and trends of liver cancer (LC) in China. Methods: We retrieved data from the Global Burden of Disease database 2019. Joinpoint regression was used to examine the temporal trend of LC. Future trends of LC were estimated using the Nordpred. Results: The incidence, mortality, and disability-standardized life year (DALY) rate of LC declined in China from 1990 to 2019. Among >210,000 LC cases in 2019, the LC incidences were nearly 3.15 times higher in males than in females. LC cases and LC-associated deaths were mostly found among patients aged 65 to 69 years. The proportion of LC attributable to hepatitis B decreased over time, whereas the proportions of LC attributable to hepatitis C, alcohol use, and non-alcoholic steatohepatitis increased modestly from 1990 to 2019. The majority of LC-associated deaths could be traced to four risk factors: smoking (20%), drug use (13.6%), alcohol use (11.7%), and high body mass index (10.1%). Based on the Nordpred prediction, there will be a steady decline in the incidence (39.0%) and mortality (38.3%) of liver cancer over a 25-year period from 2020 to 2044. Conclusion: The disease burden of liver cancer in China has declined over the past 30 years. However, it remains important to control liver cancer among high-risk populations, especially elderly males with obesity, alcohol use, tobacco use, and/or drug abuse.
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