Evidence mapPaperPMID 36091667Full record

ArticleMediators of inflammation2022

Yanghe Pingchuan Granules Alleviate Airway Inflammation in Bronchial Asthma and Inhibit Pyroptosis by Blocking the TLR4/NF-

Lingyu Pan, Yan Chen, Yeke Jiang, Yehong Sun, Yanquan Han, Yongzhong Wang

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Beyond Traditional Use: The Scientific Evidence for the Role ofPharmaceuticals (Basel, Switzerland) · 2025
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  4. Role and regulators of NFrontiers in pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lingyu PanThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230031 Anhui, China.ORCID https://orcid.org/0000-0002-4795-3744
Yan ChenAnhui University of Chinese Medicine, Hefei, 230012 Anhui, China.
Yeke JiangAnhui University of Chinese Medicine, Hefei, 230012 Anhui, China.
Yehong SunAnhui University of Chinese Medicine, Hefei, 230012 Anhui, China.
Yanquan HanThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230031 Anhui, China.
Yongzhong WangThe First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230031 Anhui, China.ORCID https://orcid.org/0000-0001-6813-3289
Anhui University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bronchial asthma (BA) is a chronic inflammatory disease of the airway. Previous research has shown that Yanghe Pingchuan granules (YPGs) exert a precise therapeutic effect on BA. In our previous work, we showed that YPGs improved inflammation of the airways in rat models of BA. Other studies have shown that the pathogenesis of BA is closely related to pyroptosis and that the TOLL-like receptor pathway plays a key role in the mediation of pyroptosis. Therefore, in the present study, we established a rat model of BA by applying the concept of pyroptosis and used the TLR4/NF-

Indexed as

AsthmaNF-kappa BAnimalsDrugs, Chinese HerbalInflammationPyroptosisRatsSignal TransductionToll-Like Receptor 4Drugs, Chinese HerbalNF-kappa BTlr4 protein, ratToll-Like Receptor 4yanghe

Identifiers

PMID36091667
PMCPMC9453091
OpenAlexW4294351418

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.