Evidence map›Paper›PMID 36092801›Full record

ArticleFrontiers in aging neuroscience2022

An examination of the relationship among plasma brain derived neurotropic factor, peripheral vascular function, and body composition with cognition in midlife African Americans/Black individuals.

Miranda K Traylor, Allison J Bauman, Napatsorn Saiyasit, Carl A Frizell, Benjamin D Hill, Amy R Nelson, Joshua L Keller

Abstract read
In one paragraph

Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. A peripheral perspective on brain health: vascular and skeletal muscle contributions.American journal of physiology. Heart and circulatory physiology · 2026
    Review
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miranda K TraylorIntegrative Laboratory of Exercise and Applied Physiology (iLEAP), Department of Health, Kinesiology, and Sport, College of Education and Professional Studies, University of South Alabama, Mobile, AL, United States.
Allison J BaumanDepartment of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, United States.
Napatsorn SaiyasitDepartment of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, United States.
Carl A FrizellPhysician Assistant Sciences Program, School of Graduate Studies and Research, Meharry Medical College, Nashville, TN, United States.
Benjamin D HillDepartment of Psychology, College of Arts and Sciences, University of South Alabama, Mobile, AL, United States.
Amy R NelsonDepartment of Physiology and Cell Biology, College of Medicine, University of South Alabama, Mobile, AL, United States.
Joshua L KellerIntegrative Laboratory of Exercise and Applied Physiology (iLEAP), Department of Health, Kinesiology, and Sport, College of Education and Professional Studies, University of South Alabama, Mobile, AL, United States.

Funding

Brain pericyte contractility, cerebral blood flow and blood-brain barrier integrity are impaired by normal aging and Alzheimer's disease amyloid-beta and are dependent on p75NTRR00AG058780 · NIA · UNIVERSITY OF SOUTH ALABAMA · PI NELSON, AMY R · 2020 to 2022
$716k
NIA NIH HHS L60 AG079454NIA NIH HHS R00 AG058780
6 · The paper itself

Abstract

African American/Black individuals have been excluded from several lines of prominent neuroscience research, despite exhibiting disproportionately higher risk factors associated with the onset and magnitude of neurodegeneration. Therefore, the objective of the current investigation was to examine potential relationships among brain derived neurotropic factor (BDNF), peripheral vascular function, and body composition with cognition in a sample of midlife, African American/Black individuals. Midlife adults (men:

Indexed as

Alzheimer’s diseasebody compositionbrain derived neurotropic factorcognitionexercisehealth disparities

Identifiers

PMID36092801
PMCPMC9453229

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.