Evidence map›Paper›PMID 36094888›Full record

ArticleThe Journal of physiology2023

Mechanisms of spontaneous Ca

Xianwei Zhang, Haibo Ni, Stefano Morotti, Charlotte E R Smith, Daisuke Sato, William E Louch, Andrew G Edwards, Eleonora Grandi

Open access · greenAbstract read
In one paragraph

Article in The Journal of physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Review
  3. Mechanisms underlying local CaThe Journal of physiology · 2025
    Article
  4. Article
  5. Review
  6. Enhanced CaJACC. Clinical electrophysiology · 2024
    Article
  7. Article
  8. Dual effects of the small-conductance CaAmerican journal of physiology. Heart and circulatory physiology · 2023
    Article
  9. Article
  10. Mechanisms of spontaneous CaThe Journal of physiology · 2023
    Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Xianwei ZhangDepartment of Pharmacology, University of California Davis, Davis, CA, USA.
Haibo NiDepartment of Pharmacology, University of California Davis, Davis, CA, USA.
Stefano MorottiDepartment of Pharmacology, University of California Davis, Davis, CA, USA.
Charlotte E R SmithDepartment of Pharmacology, University of California Davis, Davis, CA, USA.
Daisuke SatoDepartment of Pharmacology, University of California Davis, Davis, CA, USA.
William E LouchInstitute for Experimental Medical Research, Oslo University Hospital and University of Oslo, Oslo, Norway.
Andrew G EdwardsDepartment of Pharmacology, University of California Davis, Davis, CA, USA.
Eleonora GrandiDepartment of Pharmacology, University of California Davis, Davis, CA, USA.
University of California, Davis · USInstitutt for Eksperimentell Medisinsk Forskning · NOSimula Research Laboratory · NO

Funding

Project 3 (Mercola)P01HL141084 · NHLBI · STANFORD UNIVERSITY · PI MARK MERCOLA · 2019 to 2026
$21.1M
Development of the Predictive NeuroCardiovascular SimulatorOT2OD026580 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CLANCY, COLLEEN E, GRANDI, ELEONORA · 2018 to 2021
$5.7M
Sex-specific arrhythmogenic mechanisms of atrial fibrillationR01HL131517 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Eleonora Grandi · 2016 to 2026
$5.0M
Functional Microdomains in the Heart's Pacemaker: A New Dimension of Cardiac RemodelingR01HL141214 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Alexey V Glukhov · 2018 to 2026
$3.8M
Modeling of subcellular signaling crosstalk in failing myocytesR00HL138160 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MOROTTI, STEFANO · 2020 to 2022
$722k
American Heart Association Postdoctoral Fellowship 20POST35120462American Heart Association Predoctoral Fellowship 20PRE35120465NHLBI NIH HHS P01 HL141084NHLBI NIH HHS R00 HL138160NHLBI NIH HHS R01 HL131517NHLBI NIH HHS R01 HL141214NIH HHS OT2 OD026580NIH/NHLBI P01HL141084NIH/NHLBI R00HL138160NIH/NHLBI R01HL131517NIH/NHLBI R01HL141214NIH Stimulating Peripheral Activity to Relieve Conditions 1OT2OD026580-01
6 · The paper itself

Abstract

Intracellular calcium (Ca

Indexed as

Atrial FibrillationHeart FailureCalciumCalcium SignalingHeart AtriaHumansMyocytes, CardiacProteinsRyanodine Receptor Calcium Release ChannelSarcoplasmic ReticulumCalciumProteinsRyanodine Receptor Calcium Release Channelarrhythmiaatrial fibrillationcalciumcardiomyocyte ultrastructurecomputational model

Identifiers

PMID36094888
PMCPMC10008525
OpenAlexW4295885173

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.