Evidence mapPaperPMID 36097032Full record

ArticleScientific reports2022

Changes in plasma free fatty acids in obese patients before and after bariatric surgery highlight alterations in lipid metabolism.

Stephen J Hierons, Kazim Abbas, Amélie I S Sobczak, Michela Cerone, Terry K Smith, Ramzi A Ajjan, Alan J Stewart

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. [Effects of bariatric surgery on glucose and lipid metabolism in obese mice: An integrated transcriptomic and LCZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stephen J HieronsSchool of Medicine, University of St Andrews, St Andrews, KY16 9TF, UK.
Kazim AbbasRenal Transplant Unit, Manchester Royal Infirmary, Manchester, UK.
Amélie I S SobczakSchool of Medicine, University of St Andrews, St Andrews, KY16 9TF, UK.
Michela CeroneBiomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, UK.
Terry K SmithBiomedical Sciences Research Complex, University of St Andrews, St Andrews, KY16 9ST, UK.
Ramzi A AjjanLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Alan J StewartSchool of Medicine, University of St Andrews, St Andrews, KY16 9TF, UK. ajs21@st-andrews.ac.uk.
University of St Andrews · GBManchester Royal Infirmary · GBUniversity of Leeds · GB

Funding

British Heart Foundation FS/20/3/34956
6 · The paper itself

Abstract

Obesity is a complex disease that increases an individual's risk of developing other diseases and health-related problems. A common feature is dyslipidemia characterized by increased levels of plasma lipids, which include non-esterified fatty acids (NEFAs). The role of NEFAs in obesity-related morbidity is interesting as NEFAs constitute a reservoir of metabolic energy, are principal components of cell membranes and are precursors for signalling molecules. Bariatric surgery promotes sustained weight loss in severely obese patients, reducing the incidence and severity of co-morbidities. In this study we measure changes in circulating NEFA species in plasma samples taken from 25 obese individuals before and 9 months after Roux-en-Y gastric bypass surgery. The mean weight of the cohort reduced by 29.2% from 149.0 ± 25.1 kg pre-surgery to 105.5 ± 19.8 kg post-surgery and the BMI by 28.2% from 51.8 ± 6.3 kg/m

Indexed as

Bariatric SurgeryObesity, MorbidFatty Acids, NonesterifiedHumansLipid MetabolismObesityFatty Acids, Nonesterified

Identifiers

PMID36097032
PMCPMC9468139
OpenAlexW4295485606

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.