Evidence mapPaperPMID 36097824Full record

ArticlePediatric diabetes2022

Differences in retinopathy prevalence and associated risk factors across 11 countries in three continents: A cross-sectional study of 156,090 children and adolescents with type 1 diabetes.

Natasa Bratina, Marie Auzanneau, Niels Birkebaek, Carine de Beaufort, Valentino Cherubini, Maria E Craig, Dana Dabelea, Klemen Dovc, Sabine E Hofer, Reinhard W Holl and 11 more

Open access · hybridAbstract read
In one paragraph

Article in Pediatric diabetes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 14 institutions in 10 countries.

Natasa BratinaDepartment of Pediatric Endocrinology, Diabetes and Metabolic Diseases, University Children's Hospital, UMC Ljubljana, Ljubljana, Slovenia.ORCID 0000-0001-8185-5366
Marie AuzanneauInstitute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany.ORCID 0000-0002-5906-6579
Niels BirkebaekDepartment of Pediatric and Adolescents and Steno Diabetes Center, Aarhus, Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-6268-6464
Carine de BeaufortDepartment of Pediatric Diabetes and Endocrinology, Centre Hospitalier, Luxembourg, Luxembourg.ORCID 0000-0003-4310-6799
Valentino CherubiniDepartment of Women's and Children's Health, Salesi Hospital, Ancona, Italy.ORCID 0000-0002-7664-1475
Maria E CraigThe Children's Hospital at Westmead, Sydney, Australia.
Dana DabeleaDepartment of Epidemiology, Colorado School of Public Health, University of Colorado, Aurora, Colorado, USA.
Klemen DovcDepartment of Pediatric Endocrinology, Diabetes and Metabolic Diseases, University Children's Hospital, UMC Ljubljana, Ljubljana, Slovenia.ORCID 0000-0001-9201-2145
Sabine E HoferDepartment of Pediatrics 1, Medical University of Innsbruck, Innsbruck, Austria.ORCID 0000-0001-6778-0062
Reinhard W HollInstitute of Epidemiology and Medical Biometry, ZIBMT, University of Ulm, Ulm, Germany.
Elizabeth T JensenDepartment of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Dick MulDiabeter, Center for Pediatric and Adult Diabetes Care and Research, Rotterdam, The Netherlands.
Katrin NaglDepartment of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.ORCID 0000-0001-6489-9068
Holly RobinsonDepartment of Science and Research, Royal College of Paediatrics and Child Health, London, UK.
Ulrike SchierlohDepartment of Pediatric Diabetes and Endocrinology, Centre Hospitalier, Luxembourg, Luxembourg.ORCID 0000-0002-7644-4818
Jannet SvenssonDepartment of Pediatric and Adolescents, Copenhagen University Hospital, Herlev & Gentofte, Denmark.ORCID 0000-0002-9365-0728
Valentina TiberiDepartment of Women's and Children's Health, Salesi Hospital, Ancona, Italy.ORCID 0000-0002-2528-3276
Henk J VeezeDiabeter, Center for Pediatric and Adult Diabetes Care and Research, Rotterdam, The Netherlands.
Justin T WarnerDepartment of Paediatric Endocrinology, Children's Hospital for Wales, Cardiff, UK.
Kim C DonaghueThe Children's Hospital at Westmead, Sydney, Australia.
Australasian Diabetes Data Network (ADDN) Study Group, the Prospective Diabetes Follow-up Registry (DPV) initiative, Danish National Diabetes Registry (DanDiabKids), National Pediatric Diabetes Audit (NPDA), Region Marche Registry for Diabetes, Diabeter Diabetes Database, Slovenian Childhood Diabetes Registry, SEARCH for Diabetes in Youth Study
Centre Hospitalier de Luxembourg · LUDiabetes Australia · AUOspedali Riuniti di Ancona · ITThe University of Sydney · AUUniversität Ulm · DEUniversity of Ljubljana · SIColorado School of Public Health · USInnsbruck Medical University · ATMedical University of Vienna · ATNoah's Ark Children's Hospital for Wales · GBRoyal College of Paediatrics and Child Health · GBSteno Diabetes Centers · DKUniversity of Copenhagen · DKWake Forest University · US

Funding

NCCDPHP CDC HHS U18 DP006139NIDDK NIH HHS R01 DK127208NIDDK NIH HHS UC4 DK108173
6 · The paper itself

Abstract

objectiveTo examine the prevalence, time trends, and risk factors of diabetic retinopathy (DR) among youth with type 1 diabetes (T1D) from 11 countries (Australia, Austria, Denmark, England, Germany, Italy, Luxemburg, Netherlands, Slovenia, United States, and Wales). SUBJECTS AND

methodsData on individuals aged 10-21 years with T1D for >1 year during the period 2000-2020 were analyzed. We used a cross-sectional design using the most recent year of visit to investigate the time trend. For datasets with longitudinal data, we aggregated the variables per participant and observational year, using data of the most recent year to take the longest observation period into account. DR screening was performed through quality assured national screening programs. Multiple logistic regression models adjusted for the year of the eye examination, age, gender, minority status, and duration of T1D were used to evaluate clinical characteristics and the risk of DR.

resultsData from 156,090 individuals (47.1% female, median age 15.7 years, median duration of diabetes 5.2 years) were included. Overall, the unadjusted prevalence of any DR was 5.8%, varying from 0.0% (0/276) to 16.2% between countries. The probability of DR increased with longer disease duration (aOR

conclusionsThe prevalence of DR in this large cohort of youth with T1D varied among countries, increased with diabetes duration, decreased over time, and was associated with higher HbA1c, hypertension, and smoking.

Indexed as

Diabetes Mellitus, Type 1Diabetic RetinopathyHypertensionAdolescentChildCross-Sectional StudiesFemaleGlycated HemoglobinHumansMalePrevalenceRisk FactorsGlycated Hemoglobinadolescentschildrendiabetic retinopathytype 1 diabetes

Identifiers

PMID36097824
PMCPMC9771999
OpenAlexW4295519654

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.