Evidence map›Paper›PMID 36098216›Full record

ArticleJournal of cellular and molecular medicine2022

Mir-122 upregulation and let-7f downregulation combination: The effects on hepatic differentiation of hiPSCs on the PCL-Gel-HA nanofibrous scaffold.

Maliheh Parvanak, Zohreh Mostafavi-Pour, Masoud Soleimani, Amir Atashi, Ehsan Arefian, Elaheh Esmaeili

Open access · goldAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 1 country.

Maliheh ParvanakBiochemistry Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0003-4820-8559
Zohreh Mostafavi-PourBiochemistry Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.ORCID 0000-0002-3779-177X
Masoud SoleimaniHematology and Cell Therapy Department, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Amir AtashiStem cell and Tissue Engineering Research Center, Shahroud University of Medical Sciences, Shahroud, Iran.
Ehsan ArefianDepartment of Microbiology, School of Biology, College of Science, University of Tehran, Tehran, Iran.
Elaheh EsmaeiliStem Cell Technology Research Center, Tehran, Iran.ORCID 0000-0003-0324-9808
Shahroud University of Medical Sciences · IRShiraz University · IRShiraz University of Medical Sciences · IRStem Cell Technology Research Center · IRTarbiat Modares University · IRUniversity of Tehran · IR

Funding

Research and the Committee for Advanced Biomedical Sciences 10492Shiraz University of Medical Sciences
6 · The paper itself

Abstract

Cell therapy and tissue engineering as promising candidates for the liver transplantation dilemma are of special interest. Induced pluripotent stem cells (iPSCs) are one of the best sources in this field, but their differentiation methods to hepatocytes have remained challenging. We transduced human iPSCs (hiPSCs) with miR-122 and off-let-7f (hiPSCs

Indexed as

Induced Pluripotent Stem CellsMicroRNAsNanofibersAlbuminsalpha-FetoproteinsCaproatesDown-RegulationGelatinHumansHyaluronic AcidLactonesUp-RegulationUreaAlbuminsalpha-FetoproteinsCaproatescaprolactoneGelatinHyaluronic AcidLactonesMicroRNAsMIRN122 microRNA, humanUreahepatic differentiationinduced pluripotent stem cellslet-7fmiR-122nanofibrous scaffold

Identifiers

PMID36098216
PMCPMC9575133
OpenAlexW4295409656

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.