Evidence map›Paper›PMID 36107982›Full record

ReviewPLoS pathogens2022

Advances in understanding red blood cell modifications by Babesia.

Hassan Hakimi, Junya Yamagishi, Shin-Ichiro Kawazu, Masahito Asada

Open access · goldAbstract readReview
In one paragraph

Review in PLoS pathogens, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Acquired motility ofProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Development of apical membrane antigen-1 based ELISA kit for the diagnosis ofVeterinary research forum : an international quarterly journal · 2026
    Article
  5. Article
  6. In Vitro Monitoring of Babesia microti Infection Dynamics in Whole Blood Microenvironments.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Developmental synchrony and extraordinary multiplication rates in pathogenic organisms.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Whole genome sequence and diversity in multigene families ofFrontiers in cellular and infection microbiology · 2023
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hassan HakimiNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
Junya YamagishiDivision of Collaboration and Education, International Institute for Zoonosis Control, Hokkaido University, Sapporo, Japan.
Shin-Ichiro KawazuNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.
Masahito AsadaNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan.ORCID 0000-0003-0042-6856
Obihiro University of Agriculture and Veterinary Medicine · JPHokkaido University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Babesia are tick-borne protozoan parasites that can infect livestock, pets, wildlife animals, and humans. In the mammalian host, they invade and multiply within red blood cells (RBCs). To support their development as obligate intracellular parasites, Babesia export numerous proteins to modify the RBC during invasion and development. Such exported proteins are likely important for parasite survival and pathogenicity and thus represent candidate drug or vaccine targets. The availability of complete genome sequences and the establishment of transfection systems for several Babesia species have aided the identification and functional characterization of exported proteins. Here, we review exported Babesia proteins; discuss their functions in the context of immune evasion, cytoadhesion, and nutrient uptake; and highlight possible future topics for research and application in this field.

Indexed as

BabesiaTicksAnimalsAnimals, WildErythrocytesHumansMammalsSequence Analysis, DNA

Identifiers

PMID36107982
PMCPMC9477259
OpenAlexW4295907569

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.