Evidence map›Paper›PMID 36109666›Full record

ReviewNature reviews. Rheumatology2022

Sexual dimorphism in the prevalence, manifestation and outcomes of axial spondyloarthritis.

Rachael Stovall, Irene E van der Horst-Bruinsma, Shao-Hsien Liu, Tamara Rusman, Lianne S Gensler

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  15. [Sex-specific aspects in rheumatology].Zeitschrift fur Rheumatologie · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Rachael StovallDivision of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-0355-4020
Irene E van der Horst-BruinsmaRheumatology Department, Radboud University Medical Centre, Nijmegen, Netherlands.ORCID 0000-0002-8086-9915
Shao-Hsien LiuDepartment of Population and Quantitative Health Sciences, UMass Chan Medical School, Worcester, MA, USA.
Tamara RusmanDepartment of Rheumatology, Amsterdam UMC, VU University Medical Center, Amsterdam, Netherlands.
Lianne S GenslerDivision of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA. Lianne.Gensler@ucsf.edu.
University of California, San Francisco · USAmsterdam UMC Location Vrije Universiteit Amsterdam · NLRadboud University Nijmegen · NLUniversity of Massachusetts Chan Medical School · US

Funding

NRSA Training CoreTL1TR001871 · NCATS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KANAYA, ALKA M., SOMSOUK, MA · 2016 to 2025
$10.1M
NCATS NIH HHS TL1 TR001871
6 · The paper itself

Abstract

Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that predominantly affects the axial skeleton, although it can affect peripheral joints, and extra-musculoskeletal manifestations also occur. Historically, axSpA was thought to be a disease predominantly seen in men, although with the advent of magnetic resonance imaging techniques and advances in research, this dogma has been challenged and refuted. Sex and gender are different concepts, and both can have a role in disease. In axSpA, consideration of the influence of sex and gender on the disease phenotype is necessary to predict outcomes and to enable the development of therapeutic approaches that are best suited to individual patients.

Indexed as

Axial SpondyloarthritisSpondylarthritisSpondylitis, AnkylosingFemaleHumansMalePrevalenceSex Characteristics

Identifiers

PMID36109666
OpenAlexW4295948612

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.