Evidence map›Paper›PMID 36111306›Full record

SynthesisFrontiers in psychiatry2022

Assessment and correlates of autistic symptoms in Schizophrenia Spectrum Disorders measured with the PANSS Autism Severity Score: A systematic review.

Gabriele Nibbio, Stefano Barlati, Irene Calzavara-Pinton, Nicola Necchini, Elena Invernizzi, Dario Dell'Ovo, Jacopo Lisoni, Giacomo Deste, Antonio Vita

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in psychiatry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. What autism features in first episode psychosis? Results from a 2-year follow-up study.European archives of psychiatry and clinical neuroscience · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. International perspective on social cognition in schizophrenia: current stage and the next steps.European psychiatry : the journal of the Association of European Psychiatrists · 2025
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Gabriele NibbioDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Stefano BarlatiDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Irene Calzavara-PintonDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Nicola NecchiniDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Elena InvernizziDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Dario Dell'OvoDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Jacopo LisoniDepartment of Mental Health and Addiction Services, ASST Spedali Civili of Brescia, Brescia, Italy.
Giacomo DesteDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
Antonio VitaDepartment of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
University of Brescia · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Schizophrenia Spectrum Disorders (SSD) and Autism Spectrum Disorders (ASD) are considered separate entities, but the two spectra share important similarities, and the study of these areas of overlap represents a field of growing scientific interest. The PANSS Autism Score (PAUSS) was recently developed specifically to assess autistic symptoms in people living with SSD reliably and quickly. The aims of the present systematic review were to provide a comprehensive assessment of the use of the PAUSS scale in available literature and to systematically analyze cognitive, functional and neurobiological correlates of autistic symptoms measured with this instrument in SSD. The systematic literature search included three electronic databases (PubMed, Scopus and PsycINFO) as well as a manual search in Google Scholar and in reference lists of included papers. Screening and extraction were conducted by at least two independent reviewers. Out of 213 identified records, 22 articles referring to 15 original studies were included in the systematic review. Studies were conducted in several different countries by independent groups, showing consistent scientific interest in the use of the scale; most works focused on cognitive and functional correlates of ASD symptoms, but some also considered neurobiological features. Results of included studies showed that autistic symptoms in people with SSD are consistently associated with worse cognitive performance, especially in the social cognition domain, and with worse psychosocial functioning. However, the presence of autistic symptoms appears to also have a protective role, particularly on functioning, in subjects with more severe psychotic symptoms. Further exploring the impact of autistic symptoms could be of significant scientific and clinical interest, allowing the development of tailored interventions to improve treatment for people living with SSDs.

Indexed as

autismcognitionfunctioningneurobiologyPAUSSschizophrenia

Identifiers

PMID36111306
PMCPMC9468543
OpenAlexW4293661342

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.