ArticleInternational journal of cancer2023
Exposures to pesticides and risk of cancer: Evaluation of recent epidemiological evidence in humans and paths forward.
Article in International journal of cancer, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
48 citing papers in PubMed, 1 synthesis or guideline pooled it, 115 citations in OpenAlex.
- Dietary pesticide exposure and non-communicable diseases and mortality: a systematic review of prospective studies among adults.Environmental health : a global access science source · 2023Pooled it
- An exposomics analysis of 125 biomarkers of exposure to food contaminants and biomarkers of oxidative stress: a randomized cross-over chrononutrition trial of healthy adults.Environment international · 2025Trial
- Cumulative Dietary Risk of Pesticide Mixtures in Plant-Based Foods: Beyond Single-Compound Regulatory Compliance.Foods (Basel, Switzerland) · 2026Article
- Article
- Residential proximity to agricultural pesticide exposures during preconception and pregnancy and associations with Apgar scores in the Az-PEAR study (2006-2020).Journal of exposure science & environmental epidemiology · 2026Article
- Assessment of pesticide use patterns among farmers in the Jamuna riverside regions of Tangail and Sirajganj districts, Bangladesh.Scientific reports · 2026Article
- Early-onset colorectal cancer: a comprehensive review reframing hypotheses and defining research priorities.International journal of colorectal disease · 2026Review
- A One Health Perspective on Cancer: A Narrative Review.Medical sciences (Basel, Switzerland) · 2026Review
- Pesticides Drive Liver Diseases Through Non-Apoptotic Regulated Cell Death Pathways.Diseases (Basel, Switzerland) · 2026Review
- Global dataset of pesticide pollution and environmental quality standards for risk assessment (2010-2020).Scientific data · 2026Article
- Pesticides, Rheumatic Diseases, and Emerging Environmental Threats: A Scoping Review of Epidemiologic and Mechanistic Evidence.Rheumatic diseases clinics of North America · 2026Article
- An ecological time series study of lagged associations between pesticide use and cancer incidence in Ukraine.Frontiers in public health · 2026Article
- Editorial: Pest-smart strategies for improved eco-efficiency in agriculture, forestry and communities.Frontiers in insect science · 2026Article
- Article
- Characterization and Antifungal Activity of a Hevein-Like Peptide-Containing Extract FromInternational journal of microbiology · 2026Article
- Cancer and Environmental Xenobiotics: Mechanisms, Controversies, and Innovations.Journal of xenobiotics · 2025Review
- Effect of pesticides on breast cancer tumor.Biology direct · 2025Review
- Pesticide Exposure and Hematological Disorders-is There a Link?Indian pediatrics · 2025Article
- Environmental and Human Health Impacts of Agricultural Pesticides on BIPOC Communities in the United States: A Review from an Environmental Justice Perspective.International journal of environmental research and public health · 2025Review
- Food Safety in the Age of Climate Change: The Rising Risk of Pesticide Residues and the Role of Sustainable Adsorbent Technologies.Foods (Basel, Switzerland) · 2025Review
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Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
Abstract
Knowledge of the role in cancer etiology of environmental exposures as pesticides is a prerequisite for primary prevention. We review 63 epidemiological studies on exposure to pesticides and cancer risk in humans published from 2017 to 2021, with emphasis on new findings, methodological approaches, and gaps in the existing literature. While much of the recent evidence suggests causal relationships between pesticide exposure and cancer, the strongest evidence exists for acute myeloid leukemia (AML) and colorectal cancer (CRC), diseases in which the observed associations were consistent across several studies, including high-quality prospective studies and those using biomarkers for exposure assessment, with some observing dose-response relationships. Though high-quality studies have been published since the IARC monograph on organophosphate insecticides in 2017, there are still gaps in the literature on carcinogenic evidence in humans for a large number of pesticides. To further knowledge, we suggest leveraging new techniques and methods to increase sensitivity and precision of exposure assessment, incorporate multi-omics data, and investigate more thoroughly exposure to chemical mixtures. There is also a strong need for better and larger population-based cohort studies that include younger and nonoccupationally exposed individuals, particularly during developmental periods of susceptibility. Though the existing evidence has limitations, as always in science, there is sufficient evidence to implement policies and regulatory action that limit pesticide exposure in humans and, hence, further prevent a significant burden of cancers.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.