Evidence map›Paper›PMID 36137748›Full record

ArticleLife science alliance2022

Regulation of Liprin-α phase separation by CASK is disrupted by a mutation in its CaM kinase domain.

Debora Tibbe, Pia Ferle, Christoph Krisp, Sheela Nampoothiri, Ghayda Mirzaa, Melissa Assaf, Sumit Parikh, Kerstin Kutsche, Hans-Jürgen Kreienkamp

Open access · goldAbstract readCase Reports
In one paragraph

Article in Life science alliance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Liprin-α family proteins and their cellular functions.The Journal of biological chemistry · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Calcium/Calmodulin-Dependent Serine Protein Kinase (Animals : an open access journal from MDPI · 2023
    Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Debora TibbeInstitute for Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Pia FerleInstitute for Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Christoph KrispInstitute for Clinical Chemistry and Laboratory Medicine, Mass Spectrometric Proteomics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Sheela NampoothiriDepartment of Pediatric Genetics, Amrita Institute of Medical Sciences and Research Centre, Cochin, India.ORCID https://orcid.org/0000-0002-9575-0722
Ghayda MirzaaCenter for Integrative Brain Research, Seattle Children's Research Institute, Seattle, WA, USA.ORCID https://orcid.org/0000-0003-2648-7657
Melissa AssafBanner Children's Specialists Neurology Clinic, Glendale, AZ, USA.ORCID https://orcid.org/0000-0002-1995-7676
Sumit ParikhPediatric Neurology, Cleveland Clinic, Cleveland, OH, USA.
Kerstin KutscheInstitute for Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Hans-Jürgen KreienkampInstitute for Human Genetics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany Kreienkamp@uke.de.ORCID https://orcid.org/0000-0002-8871-9970
Universität Hamburg · DEAmrita Institute of Medical Sciences and Research Centre · INCleveland Clinic · USDermatology Specialists · USUniversity of Washington · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CASK is a unique membrane-associated guanylate kinase (MAGUK) because of its Ca

Indexed as

MicrocephalyCalmodulinCerebellar DiseasesGuanylate KinasesHEK293 CellsHumansMaleMutationX-Linked Intellectual DisabilityCalmodulinCASK kinasesGuanylate Kinases

Identifiers

PMID36137748
PMCPMC9500383
OpenAlexW4296805832

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.