Evidence map›Paper›PMID 36138929›Full record

ArticleBrain sciences2022

Olive- and Coconut-Oil-Enriched Diets Decreased Secondary Bile Acids and Regulated Metabolic and Transcriptomic Markers of Brain Injury in the Frontal Cortexes of NAFLD Pigs.

Magdalena A Maj, Tanvi R Gehani, Chad Immoos, Mikaelah S Medrano, Rob K Fanter, Christine R Strand, Hunter Glanz, Brian D Piccolo, Mohammed K Abo-Ismail, Michael R La Frano and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Magdalena A MajDepartment of Biological Sciences, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.ORCID 0000-0003-3511-3788
Tanvi R GehaniDepartment of Biomedical Engineering, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Chad ImmoosDepartment of Chemistry and Biochemistry, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Mikaelah S MedranoDepartment of Chemistry and Biochemistry, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Rob K FanterCollege of Agriculture, Food and Environmental Sciences, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Christine R StrandDepartment of Biological Sciences, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Hunter GlanzDepartment of Statistics, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Brian D PiccoloUSDA-ARS Arkansas Children's Nutrition Center, 1120 Marshall St. SLOT 512-20B, Little Rock, AR 72202, USA.ORCID 0000-0002-1789-4587
Mohammed K Abo-IsmailDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.
Michael R La FranoCal Poly Metabolomics Service Center, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.ORCID 0000-0002-2269-1688
Rodrigo ManjarínDepartment of Animal Science, California Polytechnic State University, 1 Grand Ave., San Luis Obispo, CA 93407, USA.ORCID 0000-0001-5691-1549
California Polytechnic State University · USArkansas Children's Nutrition Center · US

Funding

California State University Agriculture Research Institute 58873California State University Agriculture Research Institute 58913
6 · The paper itself

Abstract

The objective of this study was to investigate the effect of dietary fatty acid (FA) saturation and carbon chain length on brain bile acid (BA) metabolism and neuronal number in a pig model of pediatric NAFLD. Thirty 20-day-old Iberian pigs, pair-housed in pens, were randomly assigned to receive one of three hypercaloric diets for 10 weeks: (1) lard-enriched (LAR;

Indexed as

brainIberian pigsmetabolomicsneurodegenerationpediatric modeltranscriptomics

Identifiers

PMID36138929
PMCPMC9497137
OpenAlexW4294989868

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.