Evidence mapPaperPMID 36140505Full record

ReviewDiagnostics (Basel, Switzerland)2022

Role of Endomyocardial Biopsy in Diagnostics of Myocarditis.

Liga Vidusa, Oskars Kalejs, Aija Maca-Kaleja, Ilze Strumfa

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Review
  3. "Bridging the clinical, molecular and genetic perspectives on myocarditis in post-COVID-19 era".International journal of cardiology. Cardiovascular risk and prevention · 2026
    Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Prognostic value ofFrontiers in cardiovascular medicine · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Myocarditis Related to the Use of Mesalazine.Journal of medical cases · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liga VidusaDepartment of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia.
Oskars KalejsDepartment of Internal Medicine, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia.
Aija Maca-KalejaDepartment of Internal Medicine, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia.
Ilze StrumfaDepartment of Pathology, Riga Stradins University, 16 Dzirciema Street, LV-1007 Riga, Latvia.ORCID 0000-0002-7393-9524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endomyocardial biopsy as the cornerstone of diagnostics has been re-evaluated throughout the years, leaving unanswered questions on the precedence of it. The reported incidence of myocarditis has increased during the pandemic of coronavirus disease 2019 (COVID-19), reinforcing discussions on appropriate diagnostics of myocarditis. By analysis of evidence-based literature published within the last demi-decade, we aimed to summarize the most recent information in order to evaluate the current role of endomyocardial biopsy in diagnostics and management of myocarditis. For the most part, research published over the last five years showed ongoing uncertainty regarding the use, informativeness, safety and necessity of performing a biopsy. Special circumstances, such as fulminant clinical course or failure to respond to empirical treatment, were reconfirmed as justified indications, with a growing applicability of non-invasive diagnostic approaches for most other cases. We concluded that endomyocardial biopsy, if performed properly and with adjunct diagnostic methods, holds a critical role for treatment correction in specific histological subtypes of myocarditis and for differential diagnosis between immune-mediated myocarditis and secondary infections due to immunosuppressive treatment. A high level of possible misdiagnosing was detected, indicating the need to review terminology used to describe findings of myocardial inflammation that did not meet Dallas criteria.

Indexed as

COVID-19endomyocardial biopsyinflammatory cardiomyopathymyocarditis

Identifiers

PMID36140505
PMCPMC9497694

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.