Evidence map›Paper›PMID 36140776›Full record

ArticleGenes2022

Identification and Quantitation of Novel

Andrew K Turner, Benjamin C Shaw, James F Simpson, Steven Estus

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Aberrant phase separation from a rare ABI3 mutation drives microglial dysfunction and Alzheimer's risk.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Abi3Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Review
  4. Review
  5. Expression ofGenes · 2023
    Article
  6. The effect ofFrontiers in immunology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Andrew K TurnerDepartment of Physiology and Sanders-Brown Center on Aging, University of Kentucky, 789 S Limestone St., Lexington, KY 405361, USA.
Benjamin C ShawDepartment of Physiology and Sanders-Brown Center on Aging, University of Kentucky, 789 S Limestone St., Lexington, KY 405361, USA.ORCID 0000-0001-8862-3840
James F SimpsonDepartment of Physiology and Sanders-Brown Center on Aging, University of Kentucky, 789 S Limestone St., Lexington, KY 405361, USA.
Steven EstusDepartment of Physiology and Sanders-Brown Center on Aging, University of Kentucky, 789 S Limestone St., Lexington, KY 405361, USA.

Funding

Translating SHIP1 Genetics to Generate a Novel Alzheimers Pharmacologic AgentRF1AG059717 · NIA · UNIVERSITY OF KENTUCKY · PI ESTUS, STEVEN, HUMPHREY, MARY BETH · 2018 to 2019
$3.9M
How does D2-CD33 reduce Alzheimer's disease risk?R21AG068370 · NIA · UNIVERSITY OF KENTUCKY · PI ESTUS, STEVEN · 2020 to 2020
$421k
Translating Genetic Risk Factors to Therapies: From Big Data to Druggable TargetsK00NS120365 · NINDS · CLEVELAND CLINIC LERNER COM-CWRU · PI SHAW, BENJAMIN C. · 2022 to 2024
$253k
Translating Genetic Risk Factors to Therapies: From Big Data to Druggable TargetsF99NS120365 · NINDS · UNIVERSITY OF KENTUCKY · PI SHAW, BENJAMIN C. · 2021 to 2021
$39k
NIA NIH HHS R21 AG068370NIA NIH HHS RF1 AG059717NINDS NIH HHS F99 NS120365NINDS NIH HHS K00 NS120365
6 · The paper itself

Abstract

Elucidating the actions of genetic polymorphisms associated with the risk of Alzheimer's disease (AD) may provide novel insights into underlying mechanisms. Two polymorphisms have implicated

Indexed as

Alzheimer DiseaseAdaptor Proteins, Signal TransducingAnimalsBrainHumansMiceMicrogliaNervous System DiseasesProtein AggregatesProtein IsoformsABI3 protein, humanAbi-3 protein, mouseAdaptor Proteins, Signal TransducingProtein AggregatesProtein IsoformsAlzheimer’s diseasegeneticsmicrogliapolymorphismRNA splicing

Identifiers

PMID36140776
PMCPMC9498898

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.