Evidence map›Paper›PMID 36142158›Full record

ArticleInternational journal of molecular sciences2022

The Chromatin-Oxygen Sensor Gene

Denise Drongitis, Lucia Verrillo, Pasqualino De Marinis, Pasquale Orabona, Agnese Caiola, Giacinto Turitto, Alessandra Alfieri, Sara Bruscella, Marisa Gentile, Vania Moriello and 5 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Denise DrongitisInstitute of Genetics and Biophysics Adriano Buzzati-Traverso, CNR, 80131 Naples, Italy.
Lucia VerrilloInstitute of Genetics and Biophysics Adriano Buzzati-Traverso, CNR, 80131 Naples, Italy.
Pasqualino De MarinisA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Neurosurgery, 81100 Caserta, Italy.
Pasquale OrabonaA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Pathology, 81100 Caserta, Italy.
Agnese CaiolaA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Pathology, 81100 Caserta, Italy.
Giacinto TurittoA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Oncology, 81100 Caserta, Italy.
Alessandra AlfieriA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Neurosurgery, 81100 Caserta, Italy.
Sara BruscellaA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Neurosurgery, 81100 Caserta, Italy.
Marisa GentileA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Neurosurgery, 81100 Caserta, Italy.
Vania MorielloA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Neurosurgery, 81100 Caserta, Italy.
Ettore SanninoA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Neurosurgery, 81100 Caserta, Italy.
Ines Di MuccioA.O.R.N. S. Anna and S. Sebastiano Hospital, Division of Neurosurgery, 81100 Caserta, Italy.
Valerio CostaInstitute of Genetics and Biophysics Adriano Buzzati-Traverso, CNR, 80131 Naples, Italy.ORCID 0000-0002-7294-6933
Maria Giuseppina MianoInstitute of Genetics and Biophysics Adriano Buzzati-Traverso, CNR, 80131 Naples, Italy.ORCID 0000-0003-1396-9673
Alberto de BellisMaria Rosaria Maglione Foundation Onlus, 80122 Naples, Italy.ORCID 0000-0002-5484-1652
Institute of Genetics and Biophysics · ITPENTA Foundation · IT

Funding

Maria Rosaria Maglione Foundation Onlus MGM#2020My First AIRC Grant (MFAG) Programme grant n. 23453SATIN-POR CAMPANIA FESR 2014/2020
6 · The paper itself

Abstract

Glioblastoma multiforme (GBM) is a fatal brain tumor without effective drug treatment. In this study, we highlight, for the first time, the contribution of chromatin remodeling gene Lysine (K)-specific demethylase 5C (

Indexed as

Brain NeoplasmsGlioblastomaBrain-Derived Neurotrophic FactorCell Line, TumorChromatinGene Expression Regulation, NeoplasticHistone DemethylasesHumansHypoxiaInterleukin-6LysineOxygenSurvivinTranscription FactorsTumor MicroenvironmentBrain-Derived Neurotrophic FactorChromatinHistone DemethylasesInterleukin-6KDM5C protein, humanLysineOxygenSurvivinTranscription Factors5-aminolevulinic acid fluorescence-guided surgery (5-ALA FGS)GBM with epilepsyglioblastoma multiformeHIF1A-KDM5C axishypoxic microenvironmentKDM5C

Identifiers

PMID36142158
PMCPMC9498997
OpenAlexW4296800426

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.