Evidence map›Paper›PMID 36142225›Full record

ArticleInternational journal of molecular sciences2022

Hemodynamics and Tissue Optical Properties in Bimodal Infarctions Induced by Middle Cerebral Artery Occlusion.

Chun-Wei Wu, Jia-Jin Chen, Chou-Ching K Lin, Chien-An Chen, Chun-Ie Wu, Ing-Shiou Hwang, Tsung-Hsun Hsieh, Bor-Shing Lin, Chih-Wei Peng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Chun-Wei WuSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0002-0566-4581
Jia-Jin ChenDepartment of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan 70101, Taiwan.
Chou-Ching K LinDepartment of Neurology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.ORCID 0000-0002-3070-5787
Chien-An ChenDepartment of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan 70101, Taiwan.
Chun-Ie WuDepartment of Biomedical Engineering, College of Engineering, National Cheng Kung University, Tainan 70101, Taiwan.
Ing-Shiou HwangInstitute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan 70101, Taiwan.
Tsung-Hsun HsiehDepartment of Physical Therapy and Graduate Institute of Rehabilitation Science, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-1794-7941
Bor-Shing LinDepartment of Computer Science and Information Engineering, National Taipei University, New Taipei City 237303, Taiwan.ORCID 0000-0003-0498-3190
Chih-Wei PengSchool of Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei 11031, Taiwan.ORCID 0000-0001-9744-4094
National Cheng Kung University · TWTaipei Medical University · TWChang Gung University · TWNational Cheng Kung University Hospital · TWNational Taipei University · TW

Funding

Ministry of Science and Technology in Taiwan 104-2314-B-006-007-MY3, 101-2221-E-006-006-MY3, 110-2314-B-038-001, 110-2811-E-038-500-MY3, 110-2314-B-305-001, 109-2314-B-305-001, 109-2221-E-305-001-MY2, 109-2221-E-038-005-MY3, and 109-2314-B-038-132.National Health Research Institutes in Taiwan EX103-10139EI
6 · The paper itself

Abstract

Various infarct sizes induced by middle cerebral artery occlusion (MCAO) generate inconsistent outcomes for stroke preclinical study. Monitoring cerebral hemodynamics may help to verify the outcome of MCAO. The aim of this study was to investigate the changes in brain tissue optical properties by frequency-domain near-infrared spectroscopy (FD-NIRS), and establish the relationship between cerebral hemodynamics and infarct variation in MCAO model. The rats were undergone transient MCAO using intraluminal filament. The optical properties and hemodynamics were measured by placing the FD-NIRS probes on the scalp of the head before, during, and at various time-courses after MCAO. Bimodal infarction severities were observed after the same 90-min MCAO condition. Significant decreases in concentrations of oxygenated hemoglobin ([HbO]) and total hemoglobin ([HbT]), tissue oxygenation saturation (StO

Indexed as

Infarction, Middle Cerebral ArteryStrokeAnimalsDisease Models, AnimalHemodynamicsOxyhemoglobinsRatsOxyhemoglobinsabsorptioncerebral blood flowcerebral hemodynamicsinterhemispheric correlation coefficientischemic strokemiddle cerebral artery occlusionnear infrared spectroscopyscattering

Identifiers

PMID36142225
PMCPMC9499323
OpenAlexW4295012301

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.