Evidence mapPaperPMID 36144709Full record

ReviewMolecules (Basel, Switzerland)2022

Nano-Based Co-Delivery System for Treatment of Rheumatoid Arthritis.

Shixin Zhang, Miaomiao Zhang, Xiangyu Li, Ge Li, Bo Yang, Xinyue Lu, Yang Gao, Fengying Sun

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Molecular origin, discovery, validation and application of neoantigens.Asian journal of pharmaceutical sciences · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shixin ZhangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Miaomiao ZhangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Xiangyu LiSchool of Life Sciences, Jilin University, Changchun 130012, China.
Ge LiSchool of Life Sciences, Jilin University, Changchun 130012, China.
Bo YangSchool of Life Sciences, Jilin University, Changchun 130012, China.
Xinyue LuSchool of Life Sciences, Jilin University, Changchun 130012, China.
Yang GaoCollege of Education and Humanities, Suzhou Vocational University, Suzhou 215104, China.
Fengying SunSchool of Life Sciences, Jilin University, Changchun 130012, China.ORCID 0000-0001-6199-9311

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A systemic autoimmune condition known as rheumatoid arthritis (RA) has a significant impact on patients' quality of life. Given the complexity of RA's biology, no single treatment can totally block the disease's progression. The combined use of co-delivery regimens integrating various diverse mechanisms has been widely acknowledged as a way to make up for the drawbacks of single therapy. These days, co-delivery systems have been frequently utilized for co-treatment, getting over drug limitations, imaging of inflammatory areas, and inducing reactions. Various small molecules, nucleic acid drugs, and enzyme-like agents intended for co-delivery are frequently capable of producing the ability to require positive outcomes. In addition, the excellent response effect of phototherapeutic agents has led to their frequent use for delivery together with chemotherapeutics. In this review, we discuss different types of nano-based co-delivery systems and their advantages, limitations, and future directions. In addition, we review the prospects and predicted challenges for the combining of phototherapeutic agents with conventional drugs, hoping to provide some theoretical support for future in-depth studies of nano-based co-delivery systems and phototherapeutic agents.

Indexed as

Arthritis, RheumatoidNucleic AcidsDrug Delivery SystemsHumansNanoparticle Drug Delivery SystemQuality of LifeNanoparticle Drug Delivery SystemNucleic Acidsco-delivery systemcombination therapydrug deliverynanoparticlesphototherapyrheumatoid arthritis (RA)

Identifiers

PMID36144709
PMCPMC9503141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.