Evidence map›Paper›PMID 36145535›Full record

ArticlePharmaceutics2022

Novel αO-conotoxin GeXIVA[1,2] Nonaddictive Analgesic with Pharmacokinetic Modelling-Based Mechanistic Assessment.

Xiaoyu Zhu, Mei Yuan, Huanbai Wang, Dongting Zhangsun, Gang Yu, Jinjing Che, Sulan Luo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xiaoyu ZhuKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China.ORCID 0000-0003-4334-6653
Mei YuanState Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Huanbai WangKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China.
Dongting ZhangsunKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China.
Gang YuState Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Jinjing CheState Key Laboratory of Toxicology and Medical Countermeasures, Beijing Institute of Pharmacology and Toxicology, Beijing 100850, China.
Sulan LuoKey Laboratory of Tropical Biological Resources, Ministry of Education, Hainan University, Haikou 570228, China.ORCID 0000-0002-9358-5970
Hainan University · CNGuangxi University · CN

Funding

Major International Joint Research Project of the National Natural Science Foundation of China 81420108028National Natural Science Foundation of China 81872794the Guangxi Science and Technology Base & Talents GUIKE AD22035948the Major Science and Technology Project of Hainan Province ZDKJ2016002
6 · The paper itself

Abstract

αO-conotoxin GeXIVA[1,2] was isolated in our laboratory from

Indexed as

mechanismnonaddictive analgesicpharmacokineticsPopPK and PK-PD modellingα9α10 nAChR inhibitorαO-conotoxin GeXIVA[1,2]

Identifiers

PMID36145535
PMCPMC9505004
OpenAlexW4293718025

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.